Research progress of clinical nutrition in inflammatory bowel disease
-
摘要:
炎症性肠病是一种病因尚不明确的慢性非特异性肠道炎性疾病, 包括溃疡性结肠炎及克罗恩病。炎症性肠病的发病机制复杂，包括遗传因素和环境因素，其中饮食是重要的环境因素之一。炎症性肠病患者通常会伴有营养不良及微量元素缺乏的表现。本文综述了近年来临床营养在炎症性肠病中的研究成果，分析了炎症性肠病的不同饮食治疗策略，为进一步研究炎症性肠病的预防与治疗策略提供参考。
Abstract:Inflammatory bowel disease is a chronic non-specific inflammatory disease of the gastrointestinal tract with unclear etiology, including ulcerative colitis and the Crohn's disease. The pathogenesis of inflammatory bowel disease is complex, involving genetic and environmental factors, and diet is one of the important environmental factors. Patients with inflammatory bowel disease often present with malnutrition and micronutrient deficiencies. This paper reviewed the research achievements of clinical nutrition in inflammatory bowel disease in recent years, analyzed the different dietary therapeutic strategies for inflammatory bowel disease, and provided reference for further research on the prevention and treatment of inflammatory bowel disease.
-
-
[1] LIMKETKAI B N, MULLIN G E, LIMSUI D, et al. Role of vitamin D in inflammatory bowel disease[J]. Nutr Clin Pract, 2017, 32(3): 337-345. doi: 10.1177/0884533616674492
[2] CHIBA M, NAKANE K, KOMATSU M. Westernized diet is the most ubiquitous environmental factor in inflammatory bowel disease[J]. Perm J, 2019, 23: 18-107.
[3] LI T, QIU Y, YANG H S, et al. Systematic review and meta-analysis: association of a pre-illness Western dietary pattern with the risk of developing inflammatory bowel disease[J]. J Dig Dis, 2020, 21(7): 362-371. doi: 10.1111/1751-2980.12910
[4] SCHREINER P, MARTINHO-GRUEBER M, STUDERUS D, et al. Nutrition in inflammatory bowel disease[J]. Digestion, 2020, 101(Suppl 1): 120-135.
[5] NARULA N, WONG E C L, DEHGHAN M, et al. Association of ultra-processed food intake with risk of inflammatory bowel disease: prospective cohort study[J]. BMJ, 2021, 374: n1554.
[6] VASSEUR P, DUGELAY E, BENAMOUZIG R, et al. Dietary patterns, ultra-processed food, and the risk of inflammatory bowel diseases in the NutriNet-santé cohort[J]. Inflamm Bowel Dis, 2021, 27(1): 65-73. doi: 10.1093/ibd/izaa018
[7] BROUSSARD J L, DEVKOTA S. The changing microbial landscape of Western society: diet, dwellings and discordance[J]. Mol Metab, 2016, 5(9): 737-742. doi: 10.1016/j.molmet.2016.07.007
[8] CUEVAS-SIERRA A, MILAGRO F I, ARANAZ P, et al. Gut microbiota differences according to ultra-processed food consumption in a Spanish population[J]. Nutrients, 2021, 13(8): 2710. doi: 10.3390/nu13082710
[9] ADOLPH T E, ZHANG J W. Diet fuelling inflammatory bowel diseases: preclinical and clinical concepts[J]. Gut, 2022, 71(12): 2574-2586. doi: 10.1136/gutjnl-2021-326575
[10] HOU J K, ABRAHAM B, EL-SERAG H. Dietary intake and risk of developing inflammatory bowel disease: a systematic review of the literature[J]. Am J Gastroenterol, 2011, 106(4): 563-573. doi: 10.1038/ajg.2011.44
[11] LEONE V, CHANG E B, DEVKOTA S. Diet, microbes, and host genetics: the perfect storm in inflammatory bowel diseases[J]. J Gastroenterol, 2013, 48(3): 315-321. doi: 10.1007/s00535-013-0777-2
[12] YAO C K, MUIR J G, GIBSON P R. Review article: insights into colonic protein fermentation, its modulation and potential health implications[J]. Aliment Pharmacol Ther, 2016, 43(2): 181-196. doi: 10.1111/apt.13456
[13] SPOOREN C E, PIERIK M J, ZEEGERS M P, et al. Review article: the association of diet with onset and relapse in patients with inflammatory bowel disease[J]. Aliment Pharmacol Ther, 2013, 38(10): 1172-1187. doi: 10.1111/apt.12501
[14] OPSTELTEN J L, DE VRIES J H M, WOOLS A, et al. Dietary intake of patients with inflammatory bowel disease: a comparison with individuals from a general population and associations with relapse[J]. Clin Nutr, 2019, 38(4): 1892-1898. doi: 10.1016/j.clnu.2018.06.983
[15] FU T, CHEN H, CHEN X J, et al. Sugar-sweetened beverages, artificially sweetened beverages and natural juices and risk of inflammatory bowel disease: a cohort study of 121, 490 participants[J]. Aliment Pharmacol Ther, 2022, 56(6): 1018-1029. doi: 10.1111/apt.17149
[16] YAN J, WANG L, GU Y, et al. Dietary patterns and gut microbiota changes in inflammatory bowel disease: current insights and future challenges[J]. Nutrients, 2022, 14(19): 4003. doi: 10.3390/nu14194003
[17] WANG F, FENG J R, GAO Q, et al. Carbohydrate and protein intake and risk of ulcerative colitis: systematic review and dose-response meta-analysis of epidemiological studies[J]. Clin Nutr, 2017, 36(5): 1259-1265. doi: 10.1016/j.clnu.2016.10.009
[18] KHADEMI Z, MILAJERDI A, LARIJANI B, et al. Dietary intake of total carbohydrates, sugar and sugar-sweetened beverages, and risk of inflammatory bowel disease: a systematic review and meta-analysis of prospective cohort studies[J]. Front Nutr, 2021, 8: 707795. doi: 10.3389/fnut.2021.707795
[19] ZENG L R, HU S, CHEN P F, et al. Macronutrient intake and risk of Crohn's disease: systematic review and dose-response meta-analysis of epidemiological studies[J]. Nutrients, 2017, 9(5): 500. doi: 10.3390/nu9050500
[20] RACINE A, CARBONNEL F, CHAN S S M, et al. Dietary patterns and risk of inflammatory bowel disease in Europe: results from the EPIC study[J]. Inflamm Bowel Dis, 2016, 22(2): 345-354. doi: 10.1097/MIB.0000000000000638
[21] SCAIOLI E, LIVERANI E, BELLUZZI A. The imbalance between n-6/n-3 polyunsaturated fatty acids and inflammatory bowel disease: a comprehensive review and future therapeutic perspectives[J]. Int J Mol Sci, 2017, 18(12): 2619. doi: 10.3390/ijms18122619
[22] CHAN S S, LUBEN R, OLSEN A, et al. Association between high dietary intake of the n-3 polyunsaturated fatty acid docosahexaenoic acid and reduced risk of Crohn's disease[J]. Aliment Pharmacol Ther, 2014, 39(8): 834-842. doi: 10.1111/apt.12670
[23] HIGASHIMURA Y, TANAKA Y, TAKAGI T, et al. Trans-unsaturated fatty acid activates NLRP3 inflammasome in macrophages and exacerbates intestinal inflammation in mice[J]. Biochem Biophys Res Commun, 2020, 529(2): 243-250. doi: 10.1016/j.bbrc.2020.06.005
[24] GE Y T, LIU W, TAO H T, et al. Effect of industrial trans-fatty acids-enriched diet on gut microbiota of C57BL/6 mice[J]. Eur J Nutr, 2019, 58(7): 2625-2638. doi: 10.1007/s00394-018-1810-2
[25] LI C, ZHANG Y H, GE Y T, et al. Comparative transcriptome and microbiota analyses provide new insights into the adverse effects of industrial trans fatty acids on the small intestine of C57BL/6 mice[J]. Eur J Nutr, 2021, 60(2): 975-987. doi: 10.1007/s00394-020-02297-y
[26] TAYYEM R F, QALQILI T R, AJEEN R, et al. Dietary patterns and the risk of inflammatory bowel disease: findings from a case-control study[J]. Nutrients, 2021, 13(6): 1889. doi: 10.3390/nu13061889
[27] KOSTOVCIKOVA K, COUFAL S, GALANOVA N, et al. Diet rich in animal protein promotes pro-inflammatory macrophage response and exacerbates colitis in mice[J]. Front Immunol, 2019, 10: 919. doi: 10.3389/fimmu.2019.00919
[28] JANTCHOU P, MOROIS S, CLAVEL-CHAPELON F, et al. Animal protein intake and risk of inflammatory bowel disease: the E3N prospective study[J]. Am J Gastroenterol, 2010, 105(10): 2195-2201. doi: 10.1038/ajg.2010.192
[29] LUGLIO G, RISPO A, IMPERATORE N, et al. Surgical prevention of anastomotic recurrence by excluding mesentery in Crohn's disease: the SuPREMe-CD study- A randomized clinical trial[J]. Ann Surg, 2020, 272(2): 210-217. doi: 10.1097/SLA.0000000000003821
[30] CHEN L L, WANG J Y, YI J, et al. Increased mucin-degrading bacteria by high protein diet leads to thinner mucus layer and aggravates experimental colitis[J]. J Gastroenterol Hepatol, 2021, 36(10): 2864-2874. doi: 10.1111/jgh.15562
[31] RUBIN K H, RASMUSSEN N F, PETERSEN I, et al. Intake of dietary fibre, red and processed meat and risk of late-onset Chronic Inflammatory Diseases: a prospective Danish study on the diet, cancer and health cohort[J]. Int J Med Sci, 2020, 17(16): 2487-2495. doi: 10.7150/ijms.49314
[32] DONG C, CHAN S S M, JANTCHOU P, et al. Meat intake is associated with a higher risk of ulcerative colitis in a large European prospective cohort study[J]. J Crohns Colitis, 2022, 16(8): 1187-1196. doi: 10.1093/ecco-jcc/jjac054
[33] NARULA N, DHILLON A, ZHANG D N, et al. Enteral nutritional therapy for induction of remission in Crohn's disease[J]. Cochrane Database Syst Rev, 2018, 4(4): CD000542.
[34] LIMKETKAI B N, GORDON M, MUTLU E A, et al. Diet therapy for inflammatory bowel diseases: a call to the dining table[J]. Inflamm Bowel Dis, 2020, 26(4): 510-514. doi: 10.1093/ibd/izz297
[35] WALL C L, DAY A S, GEARRY R B. Use of exclusive enteral nutrition in adults with Crohn's disease: a review[J]. World J Gastroenterol, 2013, 19(43): 7652-7660. doi: 10.3748/wjg.v19.i43.7652
[36] LAMB C A, KENNEDY N A, RAINE T, et al. British Society of Gastroenterology consensus guidelines on the management of inflammatory bowel disease in adults[J]. Gut, 2019, 68(Suppl 3): s1-s106. doi: 10.1136/gutjnl-2019-318484
[37] MIELE E, SHAMIR R, ALOI M, et al. Nutrition in pediatric inflammatory bowel disease: a position paper on behalf of the Porto inflammatory bowel disease group of the European society of pediatric gastroenterology, hepatology and nutrition[J]. J Pediatr Gastroenterol Nutr, 2018, 66(4): 687-708. doi: 10.1097/MPG.0000000000001896
[38] SIGALL-BONEH R, PFEFFER-GIK T, SEGAL I, et al. Partial enteral nutrition with a Crohn's disease exclusion diet is effective for induction of remission in children and young adults with Crohn's disease[J]. Inflamm Bowel Dis, 2014, 20(8): 1353-1360. doi: 10.1097/MIB.0000000000000110
[39] SZCZUBEŁEK M, POMORSKA K, KORÓLCZYK-KOWALCZYK M, et al. Effectiveness of Crohn's disease exclusion diet for induction of remission in Crohn's disease adult patients[J]. Nutrients, 2021, 13(11): 4112. doi: 10.3390/nu13114112
[40] LEVINE A, WINE E, ASSA A, et al. Crohn's disease exclusion diet plus partial enteral nutrition induces sustained remission in a randomized controlled trial[J]. Gastroenterology, 2019, 157(2): 440-450. e8. doi: 10.1053/j.gastro.2019.04.021
[41] KHALILI H, HÅKANSSON N, CHAN S S, et al. Adherence to a Mediterranean diet is associated with a lower risk of later-onset Crohn's disease: results from two large prospective cohort studies[J]. Gut, 2020, 69(9): 1637-1644. doi: 10.1136/gutjnl-2019-319505
[42] GODNY L, RESHEF L, PFEFFER-GIK T, et al. Adherence to the Mediterranean diet is associated with decreased fecal calprotectin in patients with ulcerative colitis after pouch surgery[J]. Eur J Nutr, 2020, 59(7): 3183-3190. doi: 10.1007/s00394-019-02158-3
[43] STRISCIUGLIO C, CENNI S, SERRA M R, et al. Effectiveness of Mediterranean diet's adherence in children with inflammatory bowel diseases[J]. Nutrients, 2020, 12(10): 3206. doi: 10.3390/nu12103206
[44] FIORINDI C, DINU M, GAVAZZI E, et al. Adherence to Mediterranean diet in patients with inflammatory bowel disease[J]. Clin Nutr ESPEN, 2021, 46: 416-423. doi: 10.1016/j.clnesp.2021.09.726
[45] HAGAN M, HAYEE B H, RODRIGUEZ-MATEOS A. (Poly)phenols in inflammatory bowel disease and irritable bowel syndrome: a review[J]. Molecules, 2021, 26(7): 1843. doi: 10.3390/molecules26071843
[46] LARUSSA T, IMENEO M, LUZZA F. Olive tree biophenols in inflammatory bowel disease: when bitter is better[J]. Int J Mol Sci, 2019, 20(6): 1390. doi: 10.3390/ijms20061390
[47] MOZAFFARI H, DANESHZAD E, LARIJANI B, et al. Dietary intake of fish, n-3 polyunsaturated fatty acids, and risk of inflammatory bowel disease: a systematic review and meta-analysis of observational studies[J]. Eur J Nutr, 2020, 59(1): 1-17. doi: 10.1007/s00394-019-01901-0
[48] SCAIOLI E, SARTINI A, BELLANOVA M, et al. Eicosapentaenoic acid reduces fecal levels of calprotectin and prevents relapse in patients with ulcerative colitis[J]. Clin Gastroenterol Hepatol, 2018, 16(8): 1268-1275, e2. doi: 10.1016/j.cgh.2018.01.036
[49] AMROUSY D E, ELASHRY H, SALAMAH A, et al. Adherence to the Mediterranean diet improved clinical scores and inflammatory markers in children with active inflammatory bowel disease: a randomized trial[J]. J Inflamm Res, 2022, 15: 2075-2086. doi: 10.2147/JIR.S349502
[50] GIBSON P R. History of the low FODMAP diet[J]. J Gastroenterol Hepatol, 2017, 32(Suppl 1): 5-7.
[51] ZHAN Y L, ZHAN Y A, DAI S X. Is a low FODMAP diet beneficial for patients with inflammatory bowel disease?A meta-analysis and systematic review[J]. Clin Nutr, 2018, 37(1): 123-129. doi: 10.1016/j.clnu.2017.05.019
[52] POPA S L, POP C, DUMITRASCU D L. Diet advice for Crohn's disease: FODMAP and beyond[J]. Nutrients, 2020, 12(12): 3751. doi: 10.3390/nu12123751
[53] BODINI G, ZANELLA C, CRESPI M, et al. A randomized, 6-wk trial of a low FODMAP diet in patients with inflammatory bowel disease[J]. Nutrition, 2019, 67/68: 110542. doi: 10.1016/j.nut.2019.06.023
[54] BARBALHO S M, GOULART R A, ARANÃO A L C, et al. Inflammatory bowel diseases and fermentable oligosaccharides, disaccharides, monosaccharides, and polyols: an overview[J]. J Med Food, 2018, 21(7): 633-640. doi: 10.1089/jmf.2017.0120
[55] SIMÕES C D, MAGANINHO M, SOUSA A S. FODMAPs, inflammatory bowel disease and gut microbiota: updated overview on the current evidence[J]. Eur J Nutr, 2022, 61(3): 1187-1198. doi: 10.1007/s00394-021-02755-1
[56] GIBSON P R. Use of the low-FODMAP diet in inflammatory bowel disease[J]. J Gastroenterol Hepatol, 2017, 32(Suppl 1): 40-42.
[57] GRAMMATIKOPOULOU M G, GOULIS D G, GKIOURAS K, et al. Low FODMAP diet for functional gastrointestinal symptoms in quiescent inflammatory bowel disease: a systematic review of randomized controlled trials[J]. Nutrients, 2020, 12(12): 3648. doi: 10.3390/nu12123648
[58] SHIVAPPA N, STECK S E, HURLEY T G, et al. Designing and developing a literature-derived, population-based dietary inflammatory index[J]. Public Health Nutr, 2014, 17(8): 1689-1696. doi: 10.1017/S1368980013002115
[59] TABUNG F K, SMITH-WARNER S A, CHAVARRO J E, et al. Development and validation of an empirical dietary inflammatory index[J]. J Nutr, 2016, 146(8): 1560-1570. doi: 10.3945/jn.115.228718
[60] LAMERS C R, DE ROOS N M, WITTEMAN B J M. The association between inflammatory potential of diet and disease activity: results from a cross-sectional study in patients with inflammatory bowel disease[J]. BMC Gastroenterol, 2020, 20(1): 316. doi: 10.1186/s12876-020-01435-4
[61] VAGIANOS K, SHAFER L A, WITGES K, et al. Association between change in inflammatory aspects of diet and change in IBD-related inflammation and symptoms over 1 year: the Manitoba living with IBD study[J]. Inflamm Bowel Dis, 2021, 27(2): 190-202. doi: 10.1093/ibd/izaa052
[62] MIRMIRAN P, MOSLEHI N, MORSHEDZADEH N, et al. Does the inflammatory potential of diet affect disease activity in patients with inflammatory bowel disease[J]. Nutr J, 2019, 18(1): 65. doi: 10.1186/s12937-019-0492-9
[63] OLENDZKI B C, SILVERSTEIN T D, PERSUITTE G M, et al. An anti-inflammatory diet as treatment for inflammatory bowel disease: a case series report[J]. Nutr J, 2014, 13: 5. doi: 10.1186/1475-2891-13-5
[64] CAMPMANS-KUIJPERS M J E, DIJKSTRA G. Food and food groups in inflammatory bowel disease (IBD): the design of the Groningen anti-inflammatory diet (GrAID)[J]. Nutrients, 2021, 13(4): 1067. doi: 10.3390/nu13041067
[65] BRALY K, WILLIAMSON N, SHAFFER M L, et al. Nutritional adequacy of the specific carbohydrate diet in pediatric inflammatory bowel disease[J]. J Pediatr Gastroenterol Nutr, 2017, 65(5): 533-538. doi: 10.1097/MPG.0000000000001613
[66] WAHBEH G T, WARD B T, LEE D Y, et al. Lack of mucosal healing from modified specific carbohydrate diet in pediatric patients with crohn disease[J]. J Pediatr Gastroenterol Nutr, 2017, 65(3): 289-292. doi: 10.1097/MPG.0000000000001619
[67] LEWIS J D, SANDLER R S, BROTHERTON C, et al. A randomized trial comparing the specific carbohydrate diet to a Mediterranean diet in adults with Crohn's disease[J]. Gastroenterology, 2021, 161(3): 837-852, e9. doi: 10.1053/j.gastro.2021.05.047
-
期刊类型引用(9)
1. 马雪萍，王晓丽，阿里木江·司马义，徐桂萍. 腹股沟上髂筋膜阻滞复合全身麻醉对高龄髋关节置换患者术后谵妄发生的影响. 新疆医学. 2022(02): 131-134 . 
百度学术
2. 张宏，李淑萍. 老年患者髋关节置换术后谵妄的发生现状及其相关影响因素分析. 长春中医药大学学报. 2022(10): 1155-1159 . 百度学术
3. 刘贵政，郑婷婷，杜斌. 老年髋部骨折患者术后谵妄发生现况及危险因素研究. 贵州医药. 2022(09): 1405-1406 . 百度学术
4. 王秀环，鲍乐乐，马漪洁，陈宁宁. 不同麻醉方法对老年髋关节置换患者术后谵妄发生的影响. 广州医科大学学报. 2021(02): 40-44 . 百度学术
5. 刘丹，杨万翔. 人文关怀护理对人工髋关节置换术后谵妄患者临床症状的影响. 中国当代医药. 2021(25): 270-272+276 . 百度学术
6. 陈立红，徐芙蓉，叶洁玉，许华亮. 高龄骨科髋关节置换术后患者发生谵妄的危险因素分析. 现代医学与健康研究电子杂志. 2021(23): 115-118 . 百度学术
7. 毛俊岚. 高龄患者髋关节置换术后谵妄1例的护理. 基层医学论坛. 2020(03): 420-421 . 百度学术
8. 欧玉琼，吴建颖，周嫦娥. 以临床路径为指导的谵妄管理对老年股骨头置换术后患者的影响. 护理实践与研究. 2020(02): 86-88 . 百度学术
9. 姜红卫. 骨科老年患者髋关节术后谵妄发生原因及疼痛干预护理进展. 系统医学. 2020(13): 196-198 . 百度学术
其他类型引用(1)
计量
- 文章访问数: 124
- HTML全文浏览量: 35
- PDF下载量: 17
- 被引次数: 10
下载:
苏公网安备 32100302010246号