Therapeutic effect of acupuncture at Gongsun and Sifeng acupoints combined with visceral acupoint tapping on pediatric mesenteric lymphadenitis of gastrointestinal heat accumulation type
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摘要:目的
分析针刺公孙、四缝穴配合脏腑点穴对小儿肠系膜淋巴结炎(胃肠结热型)的疗效以及对血清肠型脂肪酸结合蛋白(I-FABP)、血管活性肠肽(VIP)的影响。
方法选择肠系膜淋巴结炎(胃肠结热型)患儿60例为研究对象, 根据随机数字表法分为对照组(n=30, 予常规治疗+针刺公孙、四缝穴)与研究组(n=30, 在对照组基础上配合使用脏腑点穴)。比较2组临床疗效、主要症状与体征变化，并检测血清I-FABP、VIP表达水平。
结果研究组治疗总有效率高于对照组，差异有统计学意义(P < 0.05)。治疗2周后, 2组血清I-FABP水平较治疗前降低，且研究组血清I-FABP水平低于对照组，差异有统计学意义(P < 0.05); 治疗2周后, 2组血清VIP水平较治疗前升高，且研究组血清VIP水平高于对照组，差异有统计学意义(P < 0.05)。治疗2周后，研究组主要症状与体征改善程度优于对照组，差异有统计学意义(P < 0.05)。
结论针刺公孙、四缝穴配合脏腑点穴可用于治疗胃肠结热型小儿肠系膜淋巴结炎，能够调理和改善胃肠道功能，调节血清I-FABP、VI水平，缓解患儿主要症状与体征，临床可作为一种有效的治疗方法。
Abstract:ObjectiveTo analyze the curative effect of acupuncture at Gongsun, Sifeng combined with visceral acupoint tapping in children with mesenteric lymphadenitis (type of gastrointestinal heat accumulation), and its influence on serum intestinal fatty acid-binding protein (I-FABP) and vasoactive intestinal peptide (VIP).
MethodsA total of 60 children with mesenteric lymphadenitis (type of gastrointestinal heat accumulation) were selected, and were divided into control group (n=30, conventional treatment combined with acupuncture at Gongsun and Sifeng acupoints) and study group (n=30, visceral acupoint tapping on the basis of the control group) according to the random number table method. The clinical efficacy, changes of main symptoms and signs were compared, and the expression levels of serum I-FABP and VIP were detected.
ResultsThe total effective rate of the study group was higher than that of the control group(P < 0.05). After 2 weeks of treatment, the serum I-FABP levels of the two groups were lower than that before treatment, and the serum I-FABP level of the study group was lower than that of the control group (P < 0.05). After 2 weeks of treatment, the serum VIP levels of the two groups were higher than that before treatment, and the serum VIP level of the study group was higher than that of the control group (P < 0.05). After 2 weeks of treatment, the improvement of main symptoms and signs in the study group was better than that in the control group (P < 0.05).
ConclusionAcupuncture at Gongsun and Sifeng combined with visceral acupoint tapping can be used to treat children with mesenteric lymphadytis (gastrointestinal heat accumulation type), regulate and improve gastrointestinal function, adjust the level of serum I-FABP and VI, and relieve the main symptoms and signs of children, and can be used as an effective therapeutic method.
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表 1 2组血清I-FABP、VIP水平比较(x±s)
组别 n 血清肠型脂肪酸结合蛋白/(pg/mL) 血管活性肠肽/(ng/L) 治疗前 治疗2周后 治疗前 治疗2周后 对照组 30 169.79±35.32 112.35±15.67* 20.02±2.25 25.04±2.66* 研究组 30 169.24±36.34 64.24±18.41*# 20.31±2.44 27.85±3.17*# 与治疗前比较, *P < 0.05; 与对照组比较, #P < 0.05。 
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表 2 2组主要症状与体征评分比较
例 组别 n 腹痛程度 腹部压痛 食欲减退 0分 2分 4分 6分 0分 2分 4分 6分 0分 2分 4分 6分 对照组 30 5 5 9 11 6 9 7 8 9 5 6 10 研究组 30 21 5 2 2 25 2 2 1 24 3 2 1
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