慢性肺心病患者红细胞免疫功能和T淋巴细胞亚群测定的临床意义

DETERMINATION OF ERYTHROCYTE IMMUNE FUNCTIONS AND T LYMPHOCYTE SUBGROUP IN PATIENTS WITH CHRONIC PULMONARY HEART DISEASE

摘要: 采用补体致敏酵母菌血凝法及直接SPA菌体花环法分别测定54例慢性肺心病患者红细胞免疫功能及外周血T淋巴细胞亚豁免疫功能，并与31例正常人比较．结果显示：肺心病组RBC－C3bRR、CD4／CD8比值显著降低（P＜0．01），RBC－ICR、CD3、CD4也明显降低（P＜0．05）．提示肺心病患者红细胞免疫功能及T淋巴细胞亚群免疫功能均下降．上述指标有助于肺心病患者的病情判断及预后估计．

Abstract: Erythrocyte immure functions and T lymphocyte subgroup were determined in 54 patients with chronic pulmonary heart disease and in 3l healthy Persons. The results showed that in chronicpulmonary heart disease group RBC-C,bRR, CD4/CD8 were significantly lower (P 0. 01 ), and RBC-ICR, CD3, CD4 were lower (p 0. 05 ). Our findings indicate that the measurement of erythrocyte immunefunctions and T lymphocyte suhgroup were useful diagnosis in patients with chronic pulmonary heart dis-ease.