Abstract: Using CCl4 to attack the rats and to make them hepato fibrosis, we randomly divided them into several groups, apart form the normal control group, namthy Amygdalin (D), water soluble ex tractive of Radix Salviae Miltiorrhizae (F), Cordyceps (E), (D) plus (E) (G), Colchicum (C) and blank control (B). After 60 days of pretreatment, some of the culture plates were added medicine while others were not. After 24 hours of culture, the detection result changed, which showed that the inhibition of proline'intaking of posive Colchium was most effective. The water soluble extractive of Radix salviae Miltior rhizae could also cause the inhibition of, proline intaking.