不同剂量肾上腺素对心脏骤停者心肺复苏效果的影响(附71例分析)

EFFECT OF DIFFERENT-DOSE EPINEPHRINE THERAPY ON PATIENTS RESUCITATED DURING CPR(A REPORT OF 71 CASES)

摘要: 对71例心脏骤停患者行心肺复苏术的同时，给予三种不同剂量肾上腺素弹丸式静脉注射．结果大剂量肾上腺素组（0．1mg／kg／次）心律恢复率7033％，血压恢复率62．5％，呼吸恢复率41．76％，与中剂量组门．omg／首次～0.1mg／kg／次）相近．显著高于小剂量组（0．5～1．0mg／次，P＜0.05）；大剂量组存活出院率33．33％，明显高于另两组（P＜O．05）、结果提示，在对心脏骤停者进行心肺复苏时，应尽量早期使用大剂量肾上腺素。

Abstract: Seventy one patients with cardiac arrest were divided into three gr0ups according todifferent doses epinephrine (intravenous infusion, burst) during CPR. The results showed that the recoveryrates of high-dose epinephrine group (0.1mg/kg/time) were 7O. 33% in heart beat, 62. 50% in bloodpressure, 4l. 67% in respiration. The recovery rates were significantly higher than those of low-doseepinephrine gr0up (0. 5- 1. 0mg/time) (P . O5), but high-does epinephrine gr0up and middledose epinephrine group (1. 0mg/first-O. lmg/kg/time) were similar in the recovery rates- The survivalrate of high-dose epinephrine group was significantly higher than that of the three groups (33. 33M, vsl 2%, vs 9. 09 %, P 0.05 )- it is suggested that the use of high-dose epinephrine in earlier cardiac arrestcan improve the prognosis.