Abstract: Aim: To compare the effects of Propofol and Ketamine as an anacesthetic agent for pediatric intraocular surgery. Methods: Eighty cases, ASA I, ranging in age from 81 days to 12 years. Undergoing elective intraocular surgery, were randomly divided into 2 groups. The patients received Propofol 2～3 mg·kg-1 (n = 40, group Propofol) or Ketamine 1～2 mg·kg- 1 (n = 40, group Ketamine) for induction and Propofol 5～8 mg·kg - 1·h - 1 or Ketamine 5 ～10 mg·kg - 1·h -1 for maintenance of aneasthe sia respectively. Results: As compared with those in group Ketamine the intraocular tension decreased significantly in group Propofol. Times to recovery of consciousness were shorter in group Propofol than retching and vomiting during the first 24 postoperative hours in group Propofol was lower than that in group Ketamine. Conclusion: The resuluts suggest that Propofol is a suitable general aneasthetic for pediatric intraocular surgery.