黄菊液抗单纯疱疹病毒I型的实验研究

THE ANTI-HERPES SIMPLEX VIRUS I EXPERIMENTAL RESEARCH OF HUANGJU EXTRATION

摘要: 目的 :测定黄菊液在细胞培养条件下抗单纯疱疹病毒Ⅰ型 (HSV -I)的作用。方法 :将不同浓度的黄菊液以 4种方法与不同感染剂量的HSV -Ⅰ作用后 ,加入细胞培养板内观察病毒致细胞病变作用 (CPE) ,以能抑制最大病毒感染量的药物浓度为判断结果的标准。结果 :管外法和治疗法在病毒感染剂量为 2 5TCID5 0 时 ,可抑制CPE的出现。

Abstract: Objective:To examine the effect of Huangju extraction to herpes simplex virus-I (HSV-I) in cell culture. Methods:The HuangjuU extraction in different concentrations was added to HSV-I cell culture plate. The hep-2 cells were infected with HSV-I in different TCID 50 .The cell pathogenic effects(CPE) were examined.Results:Huangju extraction can inhibit CPE.