Abstract: Objective:The purpose of this study was to consider the reason, diagnosis, prophylaxis and treatment of implantation metastasis in abdominal cavity from primary liver cancer.Methods:The retrospective analysis of clinic manifestation, treatment, initial excision of the tumor and prophylaxis of 22 cases of abdominal implantation metastasis in liver cancer was carried out.Results:21 cases were treated by surgical removal. After initial removal of implantation metastasis the survival ratio of 1, 3 and 5 years was 72 7%, 27 3% and 13 6%. One case treated conservatively was died in 9 months after liver cancer operation.Conclusion:The reasons of abdominal implantation metastasis of liver cancer were: The encapsulation was destroyed by cancer.Desquamating cells of cancer were metastasized to abdominal cavity. Dissemination of metastasis by spontaneous hemorrhage of liver cancer. Iatrgenic carcinometosis. Measures for prevention: Washing abdominal cavity thoroughly. Non-tumor technique. Attention to treatment of abdominal adhensional tissue around cancer. Contaminated with cancer in abdominal cavity the chemical drug should be perfused into cavity at regular intervals. It is necessary for follow-up examination at regular intervals in order to find subclinic patient.It is the first choice and high efficiency on surgical removal and reoperation for recurrence.