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梁明华, 孙沛毅, 杨晓梅, 周杰. 肉苁蓉总苷对家兔失血性休克/再灌注损伤的治疗效应[J]. 实用临床医药杂志, 2002, (6): 516-517. DOI: 10.3969/j.issn.1672-2353.2002.06.004
引用本文: 梁明华, 孙沛毅, 杨晓梅, 周杰. 肉苁蓉总苷对家兔失血性休克/再灌注损伤的治疗效应[J]. 实用临床医药杂志, 2002, (6): 516-517. DOI: 10.3969/j.issn.1672-2353.2002.06.004
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THE THERAPEUTIC EFFECTS OF GLYCOSIDES OF CISTANCHE ON HEMORRHAGIC SHOCK/REPERFUSION INJURY IN ANIMAL EXPERIMENT[J]. Journal of Clinical Medicine in Practice, 2002, (6): 516-517. DOI: 10.3969/j.issn.1672-2353.2002.06.004
Citation: THE THERAPEUTIC EFFECTS OF GLYCOSIDES OF CISTANCHE ON HEMORRHAGIC SHOCK/REPERFUSION INJURY IN ANIMAL EXPERIMENT[J]. Journal of Clinical Medicine in Practice, 2002, (6): 516-517. DOI: 10.3969/j.issn.1672-2353.2002.06.004
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肉苁蓉总苷对家兔失血性休克/再灌注损伤的治疗效应

THE THERAPEUTIC EFFECTS OF GLYCOSIDES OF CISTANCHE ON HEMORRHAGIC SHOCK/REPERFUSION INJURY IN ANIMAL EXPERIMENT

    摘要
  • 摘要: 目的:研究肉苁蓉总苷(glycosides of cistanche, GC)对家兔失血性休克/再灌注(hemorrhagic shock/reperfusion,S/R)损伤的治疗作用.方法:应用家兔S/R模型,观察血浆中过氧化脂质(LPO)含量、丙二醛(MDA)含量、超氧化物歧化酶(SOD)活性和血栓素A2(TXA2)、前列环素(PGI2)代谢产物的浓度以及GC对上述指标的影响.结果:与假手术组比较,S/R组LPO、MDA、TXB2明显升高,SOD、6-酮-PGF1α明显降低,GC可逆转上述指标的变化.结论:GC对S/R损伤有治疗作用.

     

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