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胡震, 沈镇宙, 邵志敏. BRCA1和BRCA2基因突变相关性乳腺癌的普查和预防[J]. 实用临床医药杂志, 2003, (2): 121-123. DOI: 10.3969/j.issn.1672-2353.2003.02.007
引用本文: 胡震, 沈镇宙, 邵志敏. BRCA1和BRCA2基因突变相关性乳腺癌的普查和预防[J]. 实用临床医药杂志, 2003, (2): 121-123. DOI: 10.3969/j.issn.1672-2353.2003.02.007
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The interrelationship of BRCA1 and BRCA2 gene mutation in the survey and prevention of breast cancers[J]. Journal of Clinical Medicine in Practice, 2003, (2): 121-123. DOI: 10.3969/j.issn.1672-2353.2003.02.007
Citation: The interrelationship of BRCA1 and BRCA2 gene mutation in the survey and prevention of breast cancers[J]. Journal of Clinical Medicine in Practice, 2003, (2): 121-123. DOI: 10.3969/j.issn.1672-2353.2003.02.007
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BRCA1和BRCA2基因突变相关性乳腺癌的普查和预防

The interrelationship of BRCA1 and BRCA2 gene mutation in the survey and prevention of breast cancers

    摘要
  • 摘要: BRCA1和ARCA2基因是抑癌基因,它们主要参与DNA损伤的修复和转录的调控.这两个基因的结构和功能异常与乳腺癌的发病密切相关.BRCA1、BRCA2突变相关性乳腺癌具有发病早、双侧性等特点.基因突变携带者的乳腺癌危险度远远高于一般……

     

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