高级检索
丁亚萍, 许勤, 王建华, 沈历宗, 肇毅, 王玲, 吴文溪. 添加短链脂肪酸的TPN对术后化疗大鼠结肠粘膜细胞增殖作用的研究[J]. 实用临床医药杂志, 2006, (9): 38-41. DOI: 10.3969/j.issn.1672-2353.2006.09.012
引用本文: 丁亚萍, 许勤, 王建华, 沈历宗, 肇毅, 王玲, 吴文溪. 添加短链脂肪酸的TPN对术后化疗大鼠结肠粘膜细胞增殖作用的研究[J]. 实用临床医药杂志, 2006, (9): 38-41. DOI: 10.3969/j.issn.1672-2353.2006.09.012
shu
DING Ya-ping, XU Qin, WANG Jian-hua, SHEN Li-zong, ZHAO Yi, WANG Ling, WU Wen-xi. THE EFFECT OF TOTAL PARENTERAL NUTRITION SUPPLEMENTED WITH SHORT-CHAIN FATTYACIDS OF THE PROLIFERATION OF COLON MUCOSAL CELLS IN RATS WITH POSTOPERATIVE CHEMOTHERAPY[J]. Journal of Clinical Medicine in Practice, 2006, (9): 38-41. DOI: 10.3969/j.issn.1672-2353.2006.09.012
Citation: DING Ya-ping, XU Qin, WANG Jian-hua, SHEN Li-zong, ZHAO Yi, WANG Ling, WU Wen-xi. THE EFFECT OF TOTAL PARENTERAL NUTRITION SUPPLEMENTED WITH SHORT-CHAIN FATTYACIDS OF THE PROLIFERATION OF COLON MUCOSAL CELLS IN RATS WITH POSTOPERATIVE CHEMOTHERAPY[J]. Journal of Clinical Medicine in Practice, 2006, (9): 38-41. DOI: 10.3969/j.issn.1672-2353.2006.09.012
shu

添加短链脂肪酸的TPN对术后化疗大鼠结肠粘膜细胞增殖作用的研究

THE EFFECT OF TOTAL PARENTERAL NUTRITION SUPPLEMENTED WITH SHORT-CHAIN FATTYACIDS OF THE PROLIFERATION OF COLON MUCOSAL CELLS IN RATS WITH POSTOPERATIVE CHEMOTHERAPY

    摘要
  • 摘要: 目的 探讨添加短链脂肪酸(SCFAs)的全肠外营养(TPN)对术后化疗大鼠结肠粘膜细胞增殖作用的影响.方法 30只SD大鼠在无渣饮食2d后建立TPN和结肠吻合模型.术后随机分为TPN对照组(对照组)、化疗+TPN组(化疗组)、化疗+TPN+SCFAs组(SCFAs组),每组10只.进行实验5 d,术后第6 d留取标本采用流式细胞术分析结肠粘膜细胞周期,观察其增殖情况.结果 化疗组结肠粘膜细胞增殖期百分比(6.23±2.75)%显著低于对照组(9.81±2.78)%,P=0.014和SCFAs组(11.57±3.54)%,P=0.001;化疗组结肠粘膜细胞的增殖指数(11.87±2.61)%显著低于其他2组(20.25±7.22)%,P=0.002;(19.70±5.12)%,P=0.003.结论 添加SCFAs的TPN能促进术后化疗大鼠结肠粘膜细胞的增殖.

     

    • HTML全文
    • 参考文献(10)
    • 相关文章
    • 施引文献
  • 资源附件(0)

/

返回文章
返回