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张莉, 顾建建. 乳腺癌组织中NF-κB和HER-2的表达及意义[J]. 实用临床医药杂志, 2010, (5): 54-56. DOI: 10.3969/j.issn.1672-2353.2010.05.011
引用本文: 张莉, 顾建建. 乳腺癌组织中NF-κB和HER-2的表达及意义[J]. 实用临床医药杂志, 2010, (5): 54-56. DOI: 10.3969/j.issn.1672-2353.2010.05.011
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ZHANG Li, GU Jian-jian. Expression of nf-kb and HER-2 and its clinical significance in breast cancer[J]. Journal of Clinical Medicine in Practice, 2010, (5): 54-56. DOI: 10.3969/j.issn.1672-2353.2010.05.011
Citation: ZHANG Li, GU Jian-jian. Expression of nf-kb and HER-2 and its clinical significance in breast cancer[J]. Journal of Clinical Medicine in Practice, 2010, (5): 54-56. DOI: 10.3969/j.issn.1672-2353.2010.05.011
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乳腺癌组织中NF-κB和HER-2的表达及意义

Expression of nf-kb and HER-2 and its clinical significance in breast cancer

    摘要
  • 摘要: 目的 探讨核转录因子κB(NF-κB)和HER-2基因在乳腺癌组织中的表达及意义.方法 采用免疫组化SP法检测40例乳腺癌组织中NF-κB和HER-2的表达情况.结果 乳腺癌组织中NF-κB、HER-2的阳性表达率分别为65%和50%; NF-κB、HER-2与乳腺癌淋巴转移相关(P<0.05), 且两者间存在相关性(P<0.05).结论 乳腺癌中NF-κB、HER-2基因的表达具有相关性,在乳腺癌的发生发展中具有重要作用.

     

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