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龚芸. 阿托伐他汀联合丹参酮ⅡA磺酸钠对冠心病心绞痛患者血清脂联素、肿瘤坏死因子-α、超敏C反应蛋白水平的影响[J]. 实用临床医药杂志, 2018, (13): 24-26. DOI: 10.7619/jcmp.201813007
引用本文: 龚芸. 阿托伐他汀联合丹参酮ⅡA磺酸钠对冠心病心绞痛患者血清脂联素、肿瘤坏死因子-α、超敏C反应蛋白水平的影响[J]. 实用临床医药杂志, 2018, (13): 24-26. DOI: 10.7619/jcmp.201813007
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GONG Yun. Effect of atorvastatin combined with sodium tanshinone ⅡA on levels of APN, TNF-α and hs-CRP in patients with angina pectoris[J]. Journal of Clinical Medicine in Practice, 2018, (13): 24-26. DOI: 10.7619/jcmp.201813007
Citation: GONG Yun. Effect of atorvastatin combined with sodium tanshinone ⅡA on levels of APN, TNF-α and hs-CRP in patients with angina pectoris[J]. Journal of Clinical Medicine in Practice, 2018, (13): 24-26. DOI: 10.7619/jcmp.201813007
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阿托伐他汀联合丹参酮ⅡA磺酸钠对冠心病心绞痛患者血清脂联素、肿瘤坏死因子-α、超敏C反应蛋白水平的影响

Effect of atorvastatin combined with sodium tanshinone ⅡA on levels of APN, TNF-α and hs-CRP in patients with angina pectoris

    摘要
  • 摘要: 目的 探讨阿托伐他汀联合丹参酮ⅡA磺酸钠治疗对冠心病心绞痛患者血清脂联素(APN)、肿瘤坏死因子-α(TNF-α)、超敏C反应蛋白(hs-CRP)水平的影响.方法 选取160例冠心病心绞痛患者患者,随机分为对照组和观察组各80例.对照组患者口服阿托伐他汀片,观察组患者在对照组基础上静脉滴注丹参酮ⅡA磺酸钠注射液,2组均进行30 d的治疗.观察2组患者治疗前后血清脂质水平、APN、TNF-α以及hs-CRP水平.结果 治疗后,2组患者血清脂质水平、APN、TNF-α以及hs-CRP水平均显著改善(P＜0.05),且观察组显著优于对照组(P＜0.05);观察组患者总有效率、心绞痛发作频率和发作持续时间显著优于对照组患者(P＜0.05).结论 联合使用阿托伐他汀和丹参酮ⅡA磺酸钠治疗冠心病心绞痛患者,可以改善患者血清脂质指标,显著降低患者hs-CRP和TNF-α水平,并显著提高患者血清APN水平.

     

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