Objective  To study the effect of local oxygen therapy on wound healing in patients with chronic wound skin grafting.

  Methods  A total of 120 patients with chronic wounds receiving autologous skin transplantation in our hospital were selected as the observation objects. According to the order of admission, they were divided into combined treatment group and simple treatment group, with 60 cases in each group. Simple treatment group was treated with autologous skin transplantation, while combined treatment group was treated with local oxygen therapy on the basis of autologous skin transplantation, and was given 90 min of treatment for each time. the treatment of all patients were treated for 3 weeks. The wound healing time, healing rate, cure rate were compared and Vancouver Scar Scale scores was used to assess the healing condition of wounds in both groups.

  Results  The healing time was (19.3±3.2) d in the combined treatment group and (28.5±6.7) days in the single treatment group (P < 0.05). The wound healing rate was (93.1±6.4)% in the combination group and (85.2±2.4)% in single treatment group(P < 0.05); the cure rate was 98.3% in the combined treatment group and 75.0% in the single treatment group, and the difference was statistically significant (P < 0.05). The follow-up results showed that Vancouver Scar Scale scores in the combination group was better than single treatment group after 6 months of treatment (P < 0.05).

  Conclusion  Local oxygen therapy is an easily operated method and plays an auxiliary role in the healing of chronic wounds after autologous epidermal transplantation.