Objective  To explore the clinical nursing for patients with acute gastroduodenal perforation treated by endoscopic titanium clip block therapy.

  Methods  Eighty-six patients with acute gastroduodenal perforation treated by endoscopic titanium clip block therapy were randomly divided into routine nursing group and holistic nursing. Satisfaction degree, time of endoscopic titanium clip closure therapy, stability time of vital signs, hospital stay, heart rate before and after nursing, Self-rating Anxiety Scale (SAS) score and success rate of one-time closure therapy were compared between the two groups.

  Results  The satisfaction degree of holistic nursing group was significantly higher than that of routine nursing group (P < 0.05). After nursing, heart rate and SAS score of holistic nursing group were significantly lower than those of routine nursing group (P < 0.05). The time of endoscopic titanium clip closure therapy, stability time of vital signs and hospital stay of the holistic nursing group were significantly shorter than those of the routine nursing group (P < 0.05). The success rate of one-time closure therapy in holistic nursing group was significantly higher than that in routine nursing group (P < 0.05).

  Conclusion  The holistic nursing is effective in treating patients with acute gastroduodenal perforation, which can shorten the therapeutic time, maintain the stability of vital signs, increase the success rate of one-time therapy, alleviate the psychological disorders of patients and shorten the hospital stay.