Objective  To investigate the effect of Yiqi Yangxin Huoxue Recipe on blood lipid and hemorheological level in patients with angina pectoris differentiated as type of deficiency of Qi and Yin complicated with blood stasis.

  Methods  A total of 126 patients with angina pectoris differentiated as type of deficiency of Qi and Yin complicated with blood stasis were selected and randomly divided into experimental group (n=63) and control group (n=63). The control group was treated with conventional western medicine, while the experimental group was treated with Yiqi Yangxin Huoxue Decoction on the basis of control group. The clinical efficacy, electrocardiogram efficacy and adverse reactions of the two groups were compared. The scores of TCM symptoms, blood lipid indexes high density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C), triglyceride (TG), total cholesterol (TC), hemorheological indexes plasma viscosity, hematocrit (HCT), erythrocyte aggregation index (EAI) were compared before treatment and 1 month after treatment in both groups.

  Results  The clinical effect and electrocardiogram effect of the experimental group were significantly better than those of the control group (P < 0.05). After one month of treatment, the scores ofTCM symptoms in both groups were significantly lower than those before treatment, and the scores in the experimental group were significantly lower than those in the control group (P < 0.05). One month after treatment, the levels of HDL-C in both groups were significantly higher than those before treatment, while the levels of LDL-C, TG and TC were significantly lower than those before treatment, and the indexes in experimental group were significantly better than those in the control group (P < 0.05). One month after treatment, plasma viscosity, HCT and EAI levels in both groups were significantly lower than those before treatment, and the indexes in experimental group were significantly lower than those in the control group (P < 0.05). The incidence rate of adverse reactions in the experimental group was 9.52%, which showed no significant difference when compared to 7.94% in the control group (P>0.05).

  Conclusion  Yiqi Yangxin Huoxue Recipe can effectively relieve the clinical symptoms of patients with angina pectoris differentiated as type of deficiency of Qi and Yin complicated with blood stasis, which can improve blood lipid metabolism and hemorheology.