Abstract: With the deepening of research, the correlation between inflammatory factors and acute myocardial infarction(AMI)has been paid more and more attention. Inflammatory factors including interleukin-6(IL-6)and interleukin-17(IL-17)are the most studied factors currently, which can participate in atherosclerosis and plaque formation through a variety of ways, and lead to plaque. The instability of plaque promotes the progression of AMI patients, leading to pathological changes such as myocardial fibrosis and left ventricular remodeling. A large number of studies have shown that the detection of IL-6 and IL-17 in AMI patients can further assess the severity and prognosis of the disease, and may find new targets of AMI by clinical intervention.