Objective  To observe the effect of iRoot BP Plus in endodontic revascularization of root canal.

  Methods  A total of 80 patients with young permanent tooth pulp necrosis were enrolled in the study, and were randomly divided into observation group (n=40) and control group (n=40). The root canal revascularization was performed in both groups. The control group used mineral trioxide aggregate (MTA) to seal the upper part of the root canal, while the observation group used iRoot BP Plus to fill the upper part of the root canal. The treatment efficiency of the two groups after 6 months was observe, the deposition rates of dentin-like cementum-like tissue at 6 months and 12 months were compared.

  Results  In the observation group, 20 cases were cured after 6 months of treatment, 13 cases were improved, and 7 cases were not effective, with total effective rate of 82.5%. In the control group, 17 patients were cured after 6 months of treatment, 11 patients were improved, and 12 cases were in valid, with total effective rate of 70.0%. The effective rate of the observation group was significantly higher than that of the control group (P < 0.05). At 6 months and 12 months after treatment, the deposition rates of dentin-like tissue in the dentin surface of the observation group were significantly higher than those of the control group (P < 0.05).

  Conclusion  iRoot BP Plus has better efficacy in the treatment of young permanent teeth pulp necrosis by root canal revascularization, and it can be used as a new choice for young permanent teeth with pulp necrosis.