Abstract: Objective To study the effects of dynamic control of temperature in operating room on the core body temperature, stress response and anesthetic effect in patients undergoing liposuction surgery under general anesthesia. Methods According to random number table method, a total of 60 general anesthesia patients with liposuction surgery were divided into two groups, with 30 cases per group. The control group was given conventional temperature conserving measures, while the study group dynamic control of temperature in operating room. Patients'core body temperature, vital signs, stress reaction and anesthetic effects of two groups were observed. Results The core body temperatures of the study group were significantly higher than that of the control group at 2 h during operation(T₂)and awakening time after anaesthesia(T₃)(P<0.05). The respiratory rate and pulse rate of the study group at T₂ and T₃ were significantly lower than those of the control group(P<0.05). After intervention, the levels of adrenalin(E), norepinephrine(NE)and cortisol(COR)were significantly increased in the two groups(P<0.05), but the study group was still significantly lower than the control group(P<0.05). The eyes opening time, intubation duration, recovery time of directional force, full waking time and postanesthenia care unit(PACU)retention time in the study group were significantly shorter than those in the control group(P<0.05). Conclusion Temperature control in operating room can effectively maintain the patient's core body temperature of general anesthesia patients with liposuction surgery, stabilize vital signs, reduce stress induced injury, and promote the recovery of patients.