1例他克莫司用于肝移植患者的药学监护

Pharmaceutical care of tacrolimus in one patient with liver transplantation

摘要:
目的探讨药师在肝移植受者术后免疫抑制治疗中的作用。
方法药师参与1例肝移植术后患者的药物治疗过程，结合他克莫司血药浓度检测、基因检测结果、相关文献，对他克莫司以及与其他药物相互作用方面进行药学监护，并调整他克莫司剂量，确保患者个体化安全用药。
结果药师可通过对患者的药学监护，提出合理用药建议。
结论药师与医生协作，可提高患者用药安全性及有效性，促进合理用药。

Abstract:
Objective To investigate the role of pharmacists in immunosuppressive therapy of recipients after liver transplantation.
Methods Pharmacists participated in the drug treatment process of one patient after liver transplantation, and combined with tacrolimus plasma concentration test, gene test results and relevant literature, pharmaceutical care was conducted on tacrolimus and its drug interactions, and the dose of tacrolimus was adjusted in order to ensure the safety of individual patient medication.
Results Pharmacists could make recommendations for rational drug use through pharmaceutical care of patients.
Conclusion Cooperation between pharmacists and doctors can improve the safety and effectiveness of medication for patients, and promote rational drug use.