Abstract: Parkinson′s disease is a neurodegenerative disease mainly manifested as resting tremor, slow action, muscle rigidity and abnormal posture, its incidence rate is second only to Alzheimer's disease, and it is prevalent in people over 65 years old. Parkinson′s disease can occur under the influence of environment and genetic genes, and about 5% of patients are caused by gene mutation. At present, there are few reports about cases of autosomal recessive juvenile Parkinson′s disease in China. This study reported a case of type 2 autosomal recessive juvenile Parkinson′s disease induced by PRKN gene mutation, and analyzed its clinical manifestation, gene characteristics and treatment plan.