Abstract: Objective: To compare the effect on human hemodynamics of Gelofusiue with Ringers solution. Methods: Twenty patients scheduled for elective ulterectomy were divided into Gelofusine group (group Ⅰ) and Ringers solution group(group Ⅱ) after the conduct of epidural block. The parameters of hemodynamics were measured by non-invasive contines cardiac output mornitoring(NCCOM). Results: Cardiac Output (CO), Cardiac Index(CI), Stroke Output(SV) and Stroke index(SI) in two groups were significantly decreased when the sensory levels were finally distributed to T_6-S. Then, those were significantly increased after fast infusing Gerlofusine(500ml) in group Ⅰ, but not Ringers solution (1000ml) in group Ⅱ． Conclution: Gerlofusine as a plasma substitute is better than Ringers solution to dilate blood volume after the conduct of epidural block.