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陈传刚. 多烯磷脂酰胆碱预防乳腺癌术后化疗致肝损害的疗效观察[J]. 实用临床医药杂志, 2015, (Z1): 37-38.
引用本文: 陈传刚. 多烯磷脂酰胆碱预防乳腺癌术后化疗致肝损害的疗效观察[J]. 实用临床医药杂志, 2015, (Z1): 37-38.
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CHEN Chuangang. Clinical effects of polyene phosphatidyl choline in prevention of postoperative breast cancer chemotherapy induced liver damage[J]. Journal of Clinical Medicine in Practice, 2015, (Z1): 37-38.
Citation: CHEN Chuangang. Clinical effects of polyene phosphatidyl choline in prevention of postoperative breast cancer chemotherapy induced liver damage[J]. Journal of Clinical Medicine in Practice, 2015, (Z1): 37-38.
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多烯磷脂酰胆碱预防乳腺癌术后化疗致肝损害的疗效观察

Clinical effects of polyene phosphatidyl choline in prevention of postoperative breast cancer chemotherapy induced liver damage

    摘要
  • 摘要: 目的 观察多烯磷脂酰胆碱在预防乳腺癌术后辅助化疗致肝损害的临床疗效.方法 乳腺癌术后首次辅助化疗患者62例随机分为治疗组32例和对照组30例.2组除常规化疗药物外,治疗组在化疗首日开始每日给予多烯磷脂酰胆碱.观察2组化疗前后丙氨酸氨基转移酶(ALT)和总胆红素(TBIL)变化情况.结果 治疗前2组ALT、TBIL指标比较差异无统计学意义(P＞0.05),化疗后治疗组ALT、TBIL水平均低于对照组(P＜0.05或P＜0.01).结论 多烯磷脂酰胆碱能有效减轻乳腺癌术后化疗引起的药物性肝损害.

     

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