Advance Search
XU Yan, ZHU Chunyun. Monitoring and protection of peripheral blood cell count for nursing staffs in ward after iodine-125 implantation[J]. Journal of Clinical Medicine in Practice, 2023, 27(13): 123-126. DOI: 10.7619/jcmp.20231229
Citation: XU Yan, ZHU Chunyun. Monitoring and protection of peripheral blood cell count for nursing staffs in ward after iodine-125 implantation[J]. Journal of Clinical Medicine in Practice, 2023, 27(13): 123-126. DOI: 10.7619/jcmp.20231229
shu

Monitoring and protection of peripheral blood cell count for nursing staffs in ward after iodine-125 implantation

  • 1.

    Departmen of Tumor Intervention, Subei People's Hospital of Jiangsu Province, Yangzhou, Jiangsu, 225001

  • 2.

    Department of Gynecology and Obstetrics, Subei People's Hospital of Jiangsu Province, Yangzhou, Jiangsu, 225001

More Information
  • Received Date: April 17, 2023
  • Revised Date: June 12, 2023
  • Available Online: July 18, 2023
    Graphical Abstract
    • Abstract
  • Objective 

    To explore the effect of radiation exposure after iodine-125 implantation on the blood indicators of nursing staff in wards, and to provide basis for improving the radiation protection of nursing staff.

    Methods 

    Peripheral blood parameters of the nursing staff(experimental group) in the ward who were exposed to iodine-125 after implantation were monitored, and the blood parameters of the nursing staff(control group) in the ward without particle implantation during the same period were compared and analyzed. In addition, the results of gamma ray exposure from different angles and distances in patients after iodine-125 implantation were compared in conditions of lead shielding or lead-free shielding on the same day.

    Results 

    The results of the peripheral blood parameters in the experimental group were lower than those in the control group (P>0.05). Under the condition of lead-free shielding, the radiation dose measured at a distance of 100 cm from the puncture site was (10.6±2.6) uSv/h, which was close to the natural background radiation dose measured by γ-rays. Under the condition of lead shielding, the radiation dose measured at a distance of 15 cm was (10.4±2.0) uSv/h, which was close to the natural background radiation dose measured by γ-rays.

    Conclusion 

    After using lead shielding, post-implantation radiation exposure from iodine-125 has no significant impact on the peripheral blood parameters of the nursing staff in the ward and can effectively reduce the safe radiation distance.

    • FullText(HTML)
    • References (14)
  • [1]
    CARDOSO R M, DE SOUZA C D, ROSTELATO M E C M, et al. Highly efficient method for production of radioactive silver seed cores for brachytherapy[J]. Appl Radiat Isot, 2017, 120: 76-81. doi: 10.1016/j.apradiso.2016.11.023
    [2]
    WU Z Y, ZHANG J, SUN Y, et al. 125I seed implant brachytherapy-assisted surgery for treatment of mucoepidermoid carcinoma of parotid[J]. Brachytherapy, 2018, 17(4): S60.
    [3]
    王一青, 朱林海, 林旭, 等. CT引导下125I粒子植入术对晚期肺癌及肺转移癌的治疗作用[J]. 中国肺癌杂志, 2020, 23(6): 424-428. https://www.cnki.com.cn/Article/CJFDTOTAL-FAIZ202006005.htm
    [4]
    张楠. 碘-125放射性粒子植入治疗对肺癌化疗患者生活质量的影响[J]. 实用临床医药杂志, 2020, 24(6): 20-23. doi: 10.7619/jcmp.202006006
    [5]
    STRZELCZYK J J, DAMILAKIS J, MARX M V, et al. Facts and controversies about radiation exposure, part 2: low-level exposures and cancer risk[J]. J Am Coll Radiol, 2007, 4(1): 32-39. doi: 10.1016/j.jacr.2006.07.010
    [6]
    姜树坤, 王俊杰, 闫先瑞, 等. 放射性125I粒子植入患者术后24 h周围人员及床边剂量检测及年累积剂量预测[J]. 中国医学装备, 2020, 17(3): 14-18. https://www.cnki.com.cn/Article/CJFDTOTAL-YXZB202003004.htm
    [7]
    周媛媛, 王进, 余宁乐, 等. 江苏省2 642名放射工作人员外周血淋巴细胞染色体畸变及微核率分析[J]. 职业与健康, 2016, 32(14): 1891-1893. https://www.cnki.com.cn/Article/CJFDTOTAL-ZYJK201614006.htm
    [8]
    张俊伶, 李德冠, 路璐, 等. Vam3对辐射所致小鼠骨髓单个核细胞损伤的保护作用[J]. 中华放射医学与防护杂志, 2014(9): 676-677. https://www.cnki.com.cn/Article/CJFDTOTAL-TJYZ201401018.htm
    [9]
    陈历赛, 段宝凤, 吴志群, 等. 125I粒子植入术后放射暴露对医护人员外周血象的影响[J]. 护理研究, 2017, 31(6): 727-728. https://www.cnki.com.cn/Article/CJFDTOTAL-SXHZ201706029.htm
    [10]
    李思进, 高再荣. 放射性125I粒子植入治疗恶性实体肿瘤技术质量管理核医学专家共识(2019年版)[J]. 中华核医学与分子影像杂志, 2020, 40(11): 673-678.
    [11]
    胡欢, 杨婷. 肿瘤科护理人员对125I粒子植入的放射防护知信行调查[J]. 实用临床护理学电子杂志, 2018, 3(37): 149-149, 151. https://www.cnki.com.cn/Article/CJFDTOTAL-SLHL201837121.htm
    [12]
    SHABANI F, HASANZADEH H, EMADI A, et al. Radiation protection knowledge, attitude, and practice (KAP) in interventional radiology[J]. Oman Med J, 2018, 33(2): 141-147.
    [13]
    国家质量监督检验检疫总局. 电离辐射防护与辐射源安全基本标准: GB 18871—2002[S]. 北京: 中国标准出版社, 2004.
    [14]
    李蓓, 赵云. 125I粒子放射防护护理质量评价体系的建立及实践初探[J]. 当代护士: 下旬刊, 2018, 25(6): 118-121. https://www.cnki.com.cn/Article/CJFDTOTAL-DDHZ201806054.htm
    • Related Articles

  • Cited by

    Periodical cited type(24)

    1. 张媛昊. 分析吸入用布地奈德混悬液联合硫酸特布他林雾化吸入用溶液治疗小儿毛细支气管炎的临床疗效及对血清IL-4、IL-6、IL-8、TNF-α、IFN-γ的影响. 黑龙江医药. 2025(01): 33-37 .
    2. 木国法，李旭，龚应玲. 白细胞介素-4、瘦素、趋化素与肥胖型哮喘患儿病情程度的关系及预测哮喘控制的价值. 实用临床医药杂志. 2025(03): 108-113 . 本站查看
    3. 尹莉娜. 小儿推拿疗法联合药物雾化治疗小儿慢性持续期支气管哮喘护理研究. 航空航天医学杂志. 2024(02): 233-235 .
    4. 薛绍芬，田英，陈雅. 糜蛋白酶联合特布他林雾化治疗支气管哮喘的临床效果. 实用临床医学. 2024(02): 14-18 .
    5. 何茸茸，徐莉，刘晶晶. 特布他林联合布地奈德雾化吸入对小儿哮喘治疗的效果分析. 智慧健康. 2024(11): 77-79 .
    6. 武文会，刘琳，耿贝贝. 氨茶碱联合特布他林与沙丁胺醇对老年支气管哮喘的治疗作用. 华夏医学. 2024(04): 185-190 .
    7. 李爱平，刘敏. 布地奈德联合特布他林雾化吸入治疗小儿支气管炎的疗效及作用机制分析. 临床研究. 2024(09): 58-61 .
    8. 巫小燕，邓暄辉. 特布他林联合布地奈德治疗支气管肺炎患儿的效果及对临床症状的影响. 医学信息. 2024(20): 131-134 .
    9. 谷志勇，刘一波. 血清CKLF-1、COX-2水平对支气管哮喘患儿临床分型的价值. 国际检验医学杂志. 2023(04): 446-449 .
    10. 常婷，杜秋燕. 特布他林结合布地奈德雾化吸入治疗小儿哮喘的临床效果. 临床医学研究与实践. 2023(12): 47-50 .
    11. 王萍，罗慧，宋春莉，陈立波. 不同剂量布地奈德对儿童支气管哮喘疗效和炎症抑制的影响. 中南医学科学杂志. 2023(05): 737-740 .
    12. 闫雪. 氨溴索联合特布他林、布地奈德治疗小儿支气管肺炎的临床效果. 妇儿健康导刊. 2023(01): 132-134 .
    13. 黄莹，郑秀琴，陈岚. 特步他林并布地奈德治疗对急性支气管哮喘患者IL-5、IL-10及TNF-α的影响. 分子诊断与治疗杂志. 2022(01): 161-164 .
    14. 赵日婵，梁方华，严有敏. 布地奈德与硫酸特布他林雾化吸入对小儿哮喘患儿血清变态反应的影响. 中国医药科学. 2022(04): 88-91 .
    15. 凌媛，陈列. 特布他林联合孟鲁司特钠治疗支气管哮喘患者的临床疗效. 临床合理用药杂志. 2022(09): 36-38 .
    16. 张洪琼，闫天凌，钱军. 特布他林、孟鲁司特钠联合治疗支气管哮喘的临床效果及呼吸力学指标观察. 解放军医药杂志. 2022(06): 96-99 .
    17. 罗媛珍，戴建华. 喘可治注射液联合布地奈德混悬液雾化治疗小儿支气管哮喘的临床观察. 现代诊断与治疗. 2022(08): 1145-1147 .
    18. 余准，黄锴川，林凯. 特布他林与异丙托溴铵雾化治疗支气管哮喘中重度急性发作的疗效及对肺功能的影响. 中国处方药. 2022(07): 114-116 .
    19. 车蓬丽，崔文兰. 孟鲁司特钠联合沙美特罗替卡松治疗小儿支气管哮喘的临床效果及对免疫功能、STAT1、IRF1的影响. 临床医学研究与实践. 2022(28): 77-80 .
    20. 齐莎莎，张国伟，孟凡威，付晓梅，张宏. 细菌溶解产物胶囊联合扎鲁司特、布地奈德气雾剂治疗支气管哮喘缓解期患儿的效果观察. 医学理论与实践. 2022(23): 4057-4059 .
    21. 乐丽君. 穴位贴敷联合雾化吸入治疗小儿喘息临床分析. 湖北理工学院学报. 2021(05): 55-59 .
    22. 刁秀伟，陈勇. 布地奈德联合盐酸氨溴索雾化吸入治疗小儿支气管肺炎的临床疗效. 江西医药. 2021(09): 1465-1467 .
    23. 丰红梅，赵梦. 布地奈德雾化吸入联合家庭教育对儿童哮喘的临床疗效观察. 中国妇幼保健. 2021(23): 5454-5458 .
    24. 赵芳，刘振国，常瑛，葛莉，李芳. 肺热清颗粒联用糖皮质激素对小儿支气管哮喘氧化/抗氧化失衡的影响. 湖南师范大学学报(医学版). 2021(06): 171-174 .

    Other cited types(0)

Catalog

    Get Citation
    PDF
    XML
    Article views (145) PDF downloads (8) Cited by(24)
    Turn off MathJax
    Article Contents
    Abstract
    References

    © 2020 《实用临床医药杂志》编辑部

    Address: 江苏省扬州市江阳中路136号，扬州大学江阳路北校区14号楼201室China Pos: 225009Tel: 0514-87978917、87978989、87978807

    苏公网安备 32100302010246号

    Supported by: Beijing Renhe Information Technology Co., Ltd.   Baidu Analytics

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return