Relationship between impaired glucose tolerance and serum adiponectin, inflammatory cytokines in adolescents with simple obesity

Tam C S, Clément K, Baur L A. Obesity and lowgrade inflammation:a paediatric perspective [J]. Obesity Reviews, 2010(2):118.

McMurray R G, Zaldivar F, Galassetti P. Cellular immunity and inflammatory mediator responses to intense exercise in overweight children and adolescents [J]. Journal of Investigative Medicine, 2007(3):120.

万乃君, 米杰, 王天有. 北京市超重和肥胖学龄儿童中代谢综合征的流行特征 [J]. 中华儿科杂志, 2007(6):417.doi: 10.3760/j.issn:0578-1310.2007.06.005.

Weyer C, Bogardus C, Mott D M. The natural history of insulin secretory dysfunction and insulin resistance in the pathogenesis of type 2 diabetes mellitus [J]. Journal of Clinical Investigation, 1999.789.

Reaven G M, Chen Y D I, Hollenbeck C B. Plasma insulin, C-peptide, and proinsulin concentrations in obese and non-obese individuals with varying degrees of glucose tolerance [J]. Journal of Clinical Endocrinology and Metabolism, 1993.44.

Gerich J E. The genetic basis of type 2 diabetes mellitus:impaired insuli secretion versus impaired insulin sensitivity [J]. Endocrine Reviews, 1998.491.

DeFronzo R. Pathogenesis of type 2 diabetes:metabolic and molecular implications for identifying diabetes genes [J]. Diabetes Reviews, 1997.177.

YAMAMOTO Y, HIROSE H, SAITO I. Correlation of the adipocyte-derived protein adiponectin with insulin resistance index and serum high-density lipoprotein-cholesterol, independent of body mass index, in the Japanese population [J]. Clinical Science (London), 2002(2):137.

LINDSAY R S, FUNAHASHI T, HANSON R L. Adiponectin and development of type 2 diabetes in the Pima Indian population [J]. Lancet, 2002, (9326):57.

廖二元, 超楚生. 内分泌学 [M]. 北京:人民卫生出版社, 2001.1681.

Tuomilehto J, Lindstrom J, Eriksson J G. Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance [J]. New England Journal of Medicine, 2001.1343.

Rosenbloom A L, Joe JR, YoungRS. Emerging epidemic of type 2 diabetes in youth [J]. Diabetes Care, 1999.345.

Fagot-Compagna A, Saadine J, Flegal K M. Diabetes, impaired fasting glucose and elevated HbAlc in US adolescents:the Third National Health and Nutrition Examination Survey [J]. Diabetes Care, 2001, (Suppt5):S134.

Saad M F, Knowler W C, Pettitt D J. The natural history of impaired glucose tolerance in the Pim a Indians [J]. New England Journal of Medicine, 1988.1500.

Haffner S M, Miettinen H, Gaskill S P. Decreased insulin action and insulin secretion predict the development of impaired glucose tolerance [J]. Diabetologia, 1996.1201.