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ZHANG Zhihui, JI Bo, MU Yushu. Clinical significance of epithelial cellular adhesion molecule expression in esophageal carcinoma[J]. Journal of Clinical Medicine in Practice, 2014, (15): 32-34. DOI: 10.7619/jcmp.201415010
Citation: ZHANG Zhihui, JI Bo, MU Yushu. Clinical significance of epithelial cellular adhesion molecule expression in esophageal carcinoma[J]. Journal of Clinical Medicine in Practice, 2014, (15): 32-34. DOI: 10.7619/jcmp.201415010
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Clinical significance of epithelial cellular adhesion molecule expression in esophageal carcinoma

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  • Published Date: September 10, 2014
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  • Objective To explore the clinical significance of epithelial cellular adhesion molecule (Ep-CAM)expression in esophageal carcinoma.Methods Ep-CAM expression of in 60 cases of esophageal carcinoma、35 cases of atypical hyperplasia and 35 cases of normal esophageal mu-cosa was respectively examined by immunohistochemistry.Results Ep-CAM expression were ob-served with positive in 28.75% of atypical hyperplasia and 90.00% of esophageal carcinoma,but with no positive expression in normal esophageal mucosa.The Ep-CAM expression with positive were significantly differently between degrees of tumor differentiation(P <0.01),lymphatic metas-tasis and 3-year survival(P <0.05).Conclusion The increase of Ep-CAM expression,as a specific index,may has the potential for esophageal cancer diagnosis and prognosis.
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