Effects of batroxobin combined with edaravone on levels of vascular endothelial growth factor,homocysteine and tumor necrosis factor-α in elderly patients with cerebral infarction

Objective To explore the effects of batroxobin combined with edaravone on vascular endothelial growth factor (VEGF),homocysteine (Hcy) and tumor necrosis factor-α (TNF-α) in elderly patients with cerebral infarction.Methods A total of 140 elderly patients with acute cerebral infarction were divided into control group and observation group,70 cases in each group.The control group was given edaravone,while the observation group was given batroxobin and edaravone.The efficacy,NIHSS score,levels of serum VEGF,Hcy and TNF-α were compared.Results The total effective rate in the observation group was significantly higher than that in the control group (P ＜ 0.05).There were significant differences in NIHSS score and serum levels of VEGF,Hcy,TNF-α between two groups (P ＜ 0.05).Conclusion Batroxobin combined with edaravone is effective in the treatment of elderly patients with acute cerebral infarction.