XIAO Jing, HUANG Yuanyuan, JIANG Side, ZOU Yaobing, YAN Zongren, TANG Mingshan. Influence of early application of citalopram on motor function recovery of patients with acute cortical cerebral infarction[J]. Journal of Clinical Medicine in Practice, 2017, (7): 5-7. DOI: 10.7619/jcmp.201707002
Citation: XIAO Jing, HUANG Yuanyuan, JIANG Side, ZOU Yaobing, YAN Zongren, TANG Mingshan. Influence of early application of citalopram on motor function recovery of patients with acute cortical cerebral infarction[J]. Journal of Clinical Medicine in Practice, 2017, (7): 5-7. DOI: 10.7619/jcmp.201707002

Influence of early application of citalopram on motor function recovery of patients with acute cortical cerebral infarction

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  • Objective To explore the influence of citalopram on early recovery of motor function in patients with acute cortical infarction.Methods A total of 276 patients with acute cerebral infarction were randomly divided into observation group and control group,138 cases in each group.Patients in control group were treated with anti-platelet,blood lipid,protective nerve and rehabilitation therapy.The observation group was given citalopram hydrobromide tablets on the basis of control group.Results The incidence rate of depression in the observation group was 18.1%,which was significantly lower than 42.7% in the control group (P < 0.05).After treatment,HDRS score and NIHSS score in the observation group were significantly lower than the control group (P < 0.05).In the observation group,after treatment of 30 days and 90 days,the increasing scores of hand motor function of FMA were 4.1 ± 1.0 points and 6.5 ± 2.5 points,which were significantly higher than 1.4 ± 0.7 points and 2.5 ± 1.5 points (P < 0.05).After treatment of 30 days,the BI score of observation group was significantly higher than control group (P < 0.05).Conclusion Early application of citalopram can effectively reduce the incidence rate of post-stroke depression in patients with acute cerebral infarction,promote the recovery of motor function and improve the quality of prognosis.
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