Effect of ultrasound-guided lumbar plexus-sciaticnerve block on perioperative oxidative stress response in elderly patients with hip replacement

LI Linfeng; ZHANG Dan; YAN Lin

doi:10.7619/jcmp.201907024

Journal of Clinical Medicine in Practice > 2019 > 23(7): 91-94, 98. > DOI: 10.7619/jcmp.201907024

LI Linfeng, ZHANG Dan, YAN Lin. Effect of ultrasound-guided lumbar plexus-sciaticnerve block on perioperative oxidative stress response in elderly patients with hip replacement[J]. Journal of Clinical Medicine in Practice, 2019, 23(7): 91-94, 98. DOI: 10.7619/jcmp.201907024

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Effect of ultrasound-guided lumbar plexus-sciaticnerve block on perioperative oxidative stress response in elderly patients with hip replacement

Department of Anaesthesiology, Yangling Demonstration Zone Hospital, Xianyang, Shaanxi, 712100

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Received Date: December 12, 2018
Accepted Date: January 12, 2019
Available Online: September 09, 2020
Published Date: April 14, 2019

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Abstract

Abstract

Objective To investigate the effect of ultrasound-guided lumbar plexus-sciatic nerve block on perioperative oxidative stress response in elderly patients with hip replacement.
Methods A total of 79 elderly patients with hip replacement were divided into two groups. The control group was treated with general anesthesia, and the observation group was treated with ropivacaine for lumbar plexus-sciatic nerve block. The perioperative hemodynamics indexes and oxidative stress response indexes were compared between the two groups. The number of effective analgesic pump presses and the number of adverse reactions were recorded.
Results At the time points of before anesthesia (T₀), skin incision (T₁), 30 minutes after operation (T₂), at the end of operation (T₃) and 1 hour after operation(T₄), the hemodynamic indexes of the control group changed significantly, and the levels of indexes at T₁ were the lowest (P < 0.05). The hemodynamic indexes of the observation group did not change significantly with time, and there were no significant differences in indexes between each time point (P>0.05). The levels of serum C-reactive protein (CRP) and cortisol (COR) from T₁ to T₄ increased significantly with time in both groups (P < 0.05), norepinephrine (NE) level was the lowest at T₂ and increased significantly from T₃ to T₆ (P < 0.05). The changes of hemodynamic indexes and oxidative stress indexes in observation group were significantly smaller than those in control group at different time points (P < 0.05). Compared with the control group, the number of effective analgesic pump presses and cases with adverse reactions in the observation group were significantly less than those in the control group (P < 0.05).
Conclusion Ultrasound-guided lumbar plexus-sciatic nerve block has a high safety in hip replacement for elderly patients with femoral neck fracture, which can better stabilize hemodynamic parameters, inhibit oxidative stress reaction and reduce the using number of analgesic pump after operation.
- hip replacement,
- anesthesia,
- ultrasound,
- nerve block,
- oxidative stress reaction,
- hemodynamics

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[1]	罗琦, 刘凯. 胸腰段骨质疏松性压缩骨折再次骨折的相关因素分析[J]. 陕西医学杂志, 2017, 46(9): 1215-1216. doi: 10.3969/j.issn.1000-7377.2017.09.025
[2]	左东, 周民. 超声引导下腰丛联合骶旁坐骨神经阻滞在高龄股骨颈骨折内固定术中的应用[J]. 创伤外科杂志, 2017, 19(7): 503-507. doi: 10.3969/j.issn.1009-4237.2017.07.007
[3]	戚大春, 安新荣. 高龄患者股骨颈骨折微创关节置换与标准后入路置换术的疗效对比[J]. 中国现代医学杂志, 2016, 26(17): 81-85. doi: 10.3969/j.issn.1005-8982.2016.17.017
[4]	张湘东. 超声引导下腰丛联合坐骨神经阻滞与腰-硬联合麻醉对膝关节镜手术患者血流动力学及麻醉效果的对比[J]. 中国实用神经疾病杂志, 2015, 18(2): 109-111. doi: 10.3969/j.issn.1673-5110.2015.02.071
[5]	王建华, 张建滨, 张娟娟, 等. 超声引导下交感神经阻滞对心绞痛患者麻醉效果、心肌酶谱及血流动力学的影响[J]. 河北医药, 2018, 40(12): 1774-1778. doi: 10.3969/j.issn.1002-7386.2018.12.003
[6]	肖西峰, 姜锋, 张琬琳. 妇科腹腔镜手术与开腹手术对患者急性损伤性氧化应激反应及能量代谢的影响[J]. 陕西医学杂志, 2015, 44(8): 1015-1017. doi: 10.3969/j.issn.1000-7377.2015.08.038
[7]	冯文龙, 周炳华, 黄伟, 等. 股骨颈骨折患者氧化应激水平与骨折愈合进度和凝血功能的相关性研究[J]. 创伤外科杂志, 2018, 20(7): 544-546. doi: 10.3969/j.issn.1009-4237.2018.07.016
[8]	蔡正强, 彭兰林, 陈政, 等. 骨折后患者应激水平对凝血功能变化与骨折愈合进度的影响[J]. 中华创伤骨科杂志, 2017, 19(4): 353-356. doi: 10.3760/cma.j.issn.1671-7600.2017.04.015
[9]	王亚欣, 张彦, 谭彬彬, 等. 不同麻醉方式对老年神经外科手术患者氧化应激的影响[J]. 中华老年医学杂志, 2013, 32(4): 416-418. doi: 10.3760/cma.j.issn.0254-9026.2013.04.018
[10]	郑德利, 孟莉, 周长浩, 等. 不同麻醉方案对颅内动脉瘤介入手术患者氧化应激反应的影响[J]. 重庆医学, 2015, 44(1): 103-106. doi: 10.3969/j.issn.1671-8348.2015.01.037
[11]	李繁, 黎仕焕, 黄奕弟. 不同浓度七氟醚麻醉对大鼠氧化应激及Caspase-9表达的影响[J]. 中国现代医学杂志, 2018, 28(13): 22-28. doi: 10.3969/j.issn.1005-8982.2018.13.004
[12]	边春生, 王惠军. 子宫良性疾病患者全麻复合硬膜外麻醉行腹腔镜辅助下阴式子宫全切术对血流动力学及血清D-D、PAI-1、t-PA水平影响研究[J]. 陕西医学杂志, 2018, 47(5): 564-567. doi: 10.3969/j.issn.1000-7377.2018.05.006
[13]	肖艺敏, 李元海, 高之心. 全麻联合超声引导下椎旁神经阻滞在胸-腹腔镜食管癌根治术中的应用[J]. 临床麻醉学杂志, 2018, 34(6): 529-533. https://www.cnki.com.cn/Article/CJFDTOTAL-LCMZ201806002.htm
[14]	陈伟, 刘洋, 张毅, 等. 喉罩保留自主呼吸全麻联合臂丛神经阻滞在小儿上肢手术中的应用效果[J]. 解放军医药杂志, 2017, 29(7): 108-111. doi: 10.3969/j.issn.2095-140X.2017.07.029
[15]	齐学勤, 刘洪新, 李冬霞, 等. 超声引导腰丛-坐骨神经阻滞在老年患者单侧下肢手术中的应用[J]. 河北医药, 2015, 37(11): 1651-1653. doi: 10.3969/j.issn.1002-7386.2015.11.016
[16]	钟剑平, 何绍旋. B超引导下腰丛-坐骨神经阻滞对老年髋关节置换术应激反应及术后镇痛的影响[J]. 临床和实验医学杂志, 2017, 16(12): 1234-1237. doi: 10.3969/j.issn.1671-4695.2017.12.032
[17]	齐玲, 王成伟, 袁秀萍, 等. 高压氧预处理对TKA及THA限制性输血患者术后氧化应激反应激活的影响[J]. 海南医学院学报, 2018, 24(16): 1494-1497. https://www.cnki.com.cn/Article/CJFDTOTAL-HNYY201816009.htm

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Effect of ultrasound-guided lumbar plexus-sciaticnerve block on perioperative oxidative stress response in elderly patients with hip replacement

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