Objective To explore the clinical significance of transaminasealanine aminotransferase (ALT) and aspartate aminotransferase (AST)detection in infants with bronchiolitis infected by respiratory syncytial virus (RSV).
Methods The levels of ALT and AST were detected in 58 infants with RSV bronchiolitis and 197 infants with non-RSV bronchiolitis, and the effect of transaminase level on disease severity were compared between the two groups.
Results There were no significant differences in levels of ALT and AST between the RSV group and the non-RSV group (P>0.05), but the proportion of infants with increased transaminase in the RSV group was significantly higher than that in the non-RSV group (P < 0.05). In the RSV group, the cases with ventilator and hospital stay in infants with increased transaminase were significantly higher and longer than those in the infants with normal transaminase (P < 0.05).
Conclusion Increased transaminase level is associated with the severity of RSV bronchiolitis in infants.
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