CHEN Li. Effect observation of probiotics combined with Kangfuxin solution on treatment of patients with mild to moderate ulcerative colitis in active stage[J]. Journal of Clinical Medicine in Practice, 2019, 23(12): 92-95. DOI: 10.7619/jcmp.201912027
Citation: CHEN Li. Effect observation of probiotics combined with Kangfuxin solution on treatment of patients with mild to moderate ulcerative colitis in active stage[J]. Journal of Clinical Medicine in Practice, 2019, 23(12): 92-95. DOI: 10.7619/jcmp.201912027

Effect observation of probiotics combined with Kangfuxin solution on treatment of patients with mild to moderate ulcerative colitis in active stage

More Information
  • Received Date: March 22, 2019
  • Accepted Date: May 09, 2019
  • Available Online: February 22, 2021
  • Published Date: June 27, 2019
  •   Objective  To investigate the effect of probiotics combined with Kangfuxin liquid in the treatment of patients with mild to moderate ulcerative colitis in active stage.
      Methods  A total of 64 patients with mild to moderate active ulcerative colitis were randomly divided into observation group and control group. Both groups were treated with conventional therapy, the control group was treated with bifidobacterium triple viable enteral capsule, while the observation group was treated with bifidobacterium triple viable enteral capsule combined with Kangfuxin liquid for retention enema. The therapeutic effect of the two groups was compared.
      Results  The total effective rate was 93.75% in the observation group, which was significantly higher than 81.25% in the control group (P < 0.05). After treatment, the scores of TCM syndromes in the observation group were significantly lower than those in the control group (P < 0.05). After treatment, the serum C reactive protein (CRP), erythrocyte sedimentation rate (ESR), procalcitonin (PCT), fibrinogen (FIB), D-dimer (D-D) in both groups significantly improved when compared with those before treatment (P < 0.05), and the indexes in the observation group were significantly better than those in the control group (P < 0.05). The incidence rate of adverse reactions was 15.63% in the observation group and 18.75% in the control group, and there was no significant difference between two groups (P>0.05).
      Conclusion  Probiotics combined with Kangfuxin solution can effectively relieve the clinical symptoms and improve the level of serological indicators in patients with mild to moderate ulcerative colitis in active stage.
  • [1]
    顾清, 张莉, 张新星, 等. 康复新液联合美沙拉嗪对老年溃疡性结肠炎患者炎性因子、凝血功能的影响[J]. 临床合理用药杂志, 2019, 12(4): 26-27. https://www.cnki.com.cn/Article/CJFDTOTAL-PLHY201904014.htm
    [2]
    彭杏红. 益生菌联合美沙拉秦对轻、中度活动期溃疡性结肠炎患者的临床疗效观察[J]. 临床研究, 2019, 27(1): 50-51. https://www.cnki.com.cn/Article/CJFDTOTAL-LCYN201901026.htm
    [3]
    李辉标, 陈新林, 陈慕媛, 等. 康复新液联用益生菌治疗溃疡性结肠炎Meta分析[J]. 辽宁中医杂志, 2018, 45(10): 2037-2041. https://www.cnki.com.cn/Article/CJFDTOTAL-LNZY201810007.htm
    [4]
    胡颖, 陈元旺. 美沙拉嗪联合康复新液治疗活动期溃疡性结肠炎疗效及对炎症因子的影响[J]. 江西医药, 2018, 53(8): 847-849. doi: 10.3969/j.issn.1006-2238.2018.8.022
    [5]
    陈战斌, 杨晓蓓, 王环. 解毒化瘀中药联合西药治疗溃疡性结肠炎疗效及对炎性反应及高凝状态的影响[J]. 现代中西医结合杂志, 2016, 25(17): 1851-1854. doi: 10.3969/j.issn.1008-8849.2016.17.009
    [6]
    王大秀, 韩继武. 血小板、纤维蛋白原、D-二聚体与溃疡性结肠炎相关性的研究[J]. 胃肠病学, 2018, 23(8): 486-488. doi: 10.3969/j.issn.1008-7125.2018.08.008
    [7]
    陈新俊, 钟海兵. 自拟凉血止泻方口服合康复新液灌肠治疗活动期溃疡性结肠炎疗效探讨[J]. 中国中医急症, 2017, 26(3): 495-497. doi: 10.3969/j.issn.1004-745X.2017.03.039
    [8]
    陈铭诗, 杜立阳, 张杰. 复方青黛颗粒联合益生菌治疗溃疡性结肠炎的疗效观察[J]. 中国中西医结合消化杂志, 2017, 25(10): 751-754. https://www.cnki.com.cn/Article/CJFDTOTAL-ZXPW201710009.htm
    [9]
    林中钰, 陈楚华, 黄晓峰. 康复新液联合双歧杆菌四联活菌片在轻中度活动期溃疡性结肠炎患者中的治疗效果及安全性[J]. 临床医学工程, 2017, 24(10): 1369-1370. doi: 10.3969/j.issn.1674-4659.2017.10.1369
    [10]
    肖铃. 益生菌联合康复新液对于活动期轻中度溃疡性结肠炎的治疗效果分析[J]. 中国处方药, 2018, 16(2): 66-67. https://www.cnki.com.cn/Article/CJFDTOTAL-ZGCF201802048.htm
    [11]
    胡冬梅, 刘翠, 张弘. 双歧杆菌乳杆菌三联活菌片治疗溃疡性结肠炎的效果及对患者微生态学的影响[J]. 中外医学研究, 2018, 16(2): 122-123. https://www.cnki.com.cn/Article/CJFDTOTAL-YJZY201802061.htm
    [12]
    朱志槐. 双歧杆菌乳杆菌三联活菌片联合蒙脱石散治疗小儿腹泻的临床分析[J]. 当代医学, 2016, 22(23): 155-156. https://www.cnki.com.cn/Article/CJFDTOTAL-DDYI201623108.htm
    [13]
    张汉超, 耿福能, 沈咏梅, 等. 康复新液药理作用及临床应用的研究进展[J]. 中国民族民间医药, 2017, 26(3): 57-60. https://www.cnki.com.cn/Article/CJFDTOTAL-MZMJ201703021.htm
    [14]
    姜景平, 李爱民, 万文明, 等. 康复新液辅助三联疗法治疗难治性消化性溃疡的临床疗效观察[J]. 当代医学, 2017, 23(6): 30-32. https://www.cnki.com.cn/Article/CJFDTOTAL-DDYI201706014.htm
    [15]
    李毅, 刘艳, 许永攀, 等. 康复新液联合美沙拉嗪治疗溃疡性结肠炎的疗效及对血清炎性因子和T淋巴细胞亚群水平的影响[J]. 华西药学杂志, 2017, 32(1): 111-112. https://www.cnki.com.cn/Article/CJFDTOTAL-HXYO201701035.htm
    [16]
    蔡沣, 郑建军, 刘开渊, 等. 康复新液保留灌肠对慢性放射性肠炎患者免疫功能和营养水平的影响[J]. 广西医科大学学报, 2019, 36(1): 75-77. https://www.cnki.com.cn/Article/CJFDTOTAL-GXYD201901018.htm
  • Related Articles

    [1]MA Linghua, LI Jiangheng, ZHONG Liuyu, HUANG Yongquan, ZHU Maoling. Clinical characteristics of pregnant woman in advanced maternal age and effect of pregnancy tests for pregnancy risks[J]. Journal of Clinical Medicine in Practice, 2022, 26(9): 50-53. DOI: 10.7619/jcmp.20214722
    [2]CHEN Peihong, JIN Hua, ZHANG Shan, YU Xuemei, DAI Jiarong, YI Jufen. The clinical significance of blood lipid level in patientswith gestational diabetes mellitus in late pregnancy and its impact on neonates[J]. Journal of Clinical Medicine in Practice, 2019, 23(17): 96-98, 102. DOI: 10.7619/jcmp.201917027
    [3]ZHAO Yingwu, FU Ting. Clinical exploration on surgical methods for typeⅡ cesarean scar pregnancy[J]. Journal of Clinical Medicine in Practice, 2019, 23(15): 42-44. DOI: 10.7619/jcmp.201915011
    [4]ZHANG Feifeng, XIA Ping, LIN Hong. Clinical observation of transvaginal lesions excision in lower uterine segment scar pregnancy[J]. Journal of Clinical Medicine in Practice, 2018, (5): 116-118. DOI: 10.7619/jcmp.201805036
    [5]LI Haiyan, REN Jing, WEI Min. Clinical value of evidence-based nursing in patients with pregnancy-induced hypertension syndrome[J]. Journal of Clinical Medicine in Practice, 2017, (8): 159-161. DOI: 10.7619/jcmp.201708047
    [6]NIE Qin. Clinical study of comprehensive nursing intervention on delivery of the pregnancy with scar uterus[J]. Journal of Clinical Medicine in Practice, 2017, (4): 135-137. DOI: 10.7619/jcmp.201704041
    [7]MA Chun, TIAN Li. Influence of uterine perfusion with hCG in ovulatory period on endometrial pinopodes and clinical pregnancy rate in patients with RSA[J]. Journal of Clinical Medicine in Practice, 2016, (21): 69-71,75. DOI: 10.7619/jcmp.201621021
    [8]CAO Xin, ZHANG Yan. Clinical application value of humane care in ectopic pregnancy nursing[J]. Journal of Clinical Medicine in Practice, 2015, (22): 97-99. DOI: 10.7619/jcmp.201522032
    [9]Clinical observation on the time of termination of pregnancy and method of delivery in pregnant patients with hypertension[J]. Journal of Clinical Medicine in Practice, 2014, (5): 135-138. DOI: 10.7619/jcmp.201405047
    [10]WU Meihua, ZHANG Ying. Application of clinical nursing pathway in pregnant women with intrahepatic cholestasis[J]. Journal of Clinical Medicine in Practice, 2014, (4): 62-64. DOI: 10.7619/jcmp.201404021
  • Cited by

    Periodical cited type(9)

    1. 冯嘉伟. 宫颈液基细胞学检查与宫颈病变临床病理分析. 实用妇科内分泌电子杂志. 2024(06): 79-81 .
    2. 况漫,马亚琳,朱贵娟. 湖北十堰地区女性HPV感染分布及类型特征分析. 公共卫生与预防医学. 2023(01): 127-130 .
    3. 唐绥清. 液基细胞学检查及高危HPV检测联合阴道镜检查对宫颈癌筛查的临床意义. 中国社区医师. 2021(03): 141-142 .
    4. 付敏,陈路燕. HPV及TCT联合阴道镜活检在宫颈癌分层筛查中的临床应用价值. 当代医学. 2021(12): 74-76 .
    5. 王熙,王丽莎,杨翠,贾立云,潘雪娇,杨会欣,马翠霞,祁麟. 石家庄市育龄女性人乳头瘤病毒感染及病毒分型情况分析. 中国性科学. 2021(05): 84-87 .
    6. 田秋艳. 宫颈液基细胞学与人乳头瘤病毒检测在宫颈低级别上皮内病变中的相关性研究. 中国社区医师. 2021(29): 111-112 .
    7. 柏永华,曾丽莉,纪青. 宫颈液基细胞学检查对宫颈病变的筛查价值. 中国卫生标准管理. 2020(04): 122-124 .
    8. 刘群香,王莉,李江丽. 持续感染状态的HPV-16及HPV-58亚型在宫颈病变中的分布及危险因素. 河北医学. 2020(04): 541-545 .
    9. 唐永红,刘涛,彭健. 人乳头瘤病毒在宫颈病变中的感染分型及其特点. 系统医学. 2020(17): 134-136 .

    Other cited types(6)

Catalog

    Article views (291) PDF downloads (7) Cited by(15)

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return