Investigation on infection status of population with <i>Helicobacter pylori</i> infection in Shengyang region

GUO Ying; PEI Dongmei; ZHANG Naisi

doi:10.7619/jcmp.201913028

Journal of Clinical Medicine in Practice > 2019 > 23(13): 99-101, 105. > DOI: 10.7619/jcmp.201913028

GUO Ying, PEI Dongmei, ZHANG Naisi. Investigation on infection status of population with Helicobacter pylori infection in Shengyang region[J]. Journal of Clinical Medicine in Practice, 2019, 23(13): 99-101, 105. DOI: 10.7619/jcmp.201913028

Citation:

PDF (647 KB)

Investigation on infection status of population with Helicobacter pylori infection in Shengyang region

Department of General Medicine, Shengjing Hospital Affiliated to China Medical University, Shenyang, Liaoning, 110004

More Information

Received Date: May 14, 2019
Accepted Date: June 21, 2019
Available Online: February 23, 2021
Published Date: July 14, 2019

Graphical Abstract

Abstract

Abstract

Objective To investigate the infection status of Helicobacter pylori(Hp) infection in Shenyang region, and to analyze its infection characteristics and related factors.
Methods The data of population with Hp infection detected in our physical examination center from January to December 2018 were retrospectively studied. These patients were divided into three groups according to varied ages: the youth group, the middle-aged group and the elderly group, and two groups according to the infection conditions: Hp-positive group and negative group. The characteristics of infections in varied gender and age groups were analyzed, and relationship between Hp infection and blood glucose, blood lipids were observed.
Results ¹⁴C urea exhalation test was carried out in 11 775 people, with total infection rate of 30.99%. In the positive group, there were 2 376 male cases, and 1 273 female cases, with the infection rate of 65.11%, 34.89%, respectively, the differences were statistically significant (P < 0.05). The positive and negative rates of Hp in the young group showed significant differences compared to those in the middle-aged and elderly groups (P < 0.01), but no significant differences were seen between the middle-aged group and the elderly group (P>0.05). The blood glucose, triglyceride and low-density cholesterol levels in Hp-positive group were higher than those in Hp-negative group (P < 0.05), but there was no significant between-group differences in total cholesterol and high-density cholesterol(P>0.05).
Conclusion Hp positive infection is related to age, sex, blood glucose, triglyceride and low-density cholesterol, but has no significant correlation with total cholesterol and high-density cholesterol.
- Helicobacter pylori,
- blood glucose,
- blood lipids,
- total cholesterol,
- high density cholesterol

FullText(HTML)

References (31)

References

[1]	McGuigan A, Kelly P, Turkington R C, et al. Pancreatic cancer: A review of clinical diagnosis, epidemiology, treatment and outcomes[J]. World J Gastroenterol, 2018, 24(43): 4846-4861. doi: 10.3748/wjg.v24.i43.4846
[2]	白焕焕. 肠内营养对溃疡性结肠炎患者的疗效评价及生活质量评估[D]. 长春: 吉林大学, 2016.
[3]	Khademi F, Poursina F, Hosseini E, et al. Helicobacter pylori in Iran: A systematic review on the antibiotic resistance[J]. Iran J Basic Med Sci, 2015, 18(1): 2-7. http://pubmedcentralcanada.ca/pmcc/articles/PMC4366738/
[4]	Flores-Treviño C E, Urrutia-Baca V H, Gómez-Flores R, et al. Molecular detection of Helicobacter pylori based on the presence of cagA and vacA virulence genes in dental plaque from patients with periodontitis[J]. J Dent Sci, 2019, 14(2): 163-170. doi: 10.1016/j.jds.2019.01.010
[5]	王欢, 熊梅, 付丽, 等. 2型糖尿病患者颈动脉粥样硬化与幽门螺杆菌感染的相关性研究[J]. 临床和实验医学杂志, 2017, 16(11): 1116-1119. doi: 10.3969/j.issn.1671-4695.2017.11.025
[6]	卢学勉. 2型糖尿病患者心脑血管病变和幽门螺杆菌感染之间的关系[C]. 杭州: 浙江省医学会内分泌学分会: 浙江省科学技术协会, 2005.
[7]	Zhao Z W, Kang W M, Ma Z Q, et al. Gastric cancer with severe immune thrombocytopenia: A case report[J]. World J Clin Cases, 2018, 6(15): 1024-1028. doi: 10.12998/wjcc.v6.i15.1024
[8]	Rahmani Y, Mohammadi S, Babanejad M, et al. Association of helicobacter pylori with presence of myocardial infarction in iran: a systematic review and meta-analysis[J]. Ethiop J Health Sci, 2017, 27(4): 433-440. doi: 10.4314/ejhs.v27i4.15
[9]	Bravo D, Hoare A, Soto C, et al. Helicobacter pylori in human health and disease: Mechanisms for local gastric and systemic effects[J]. WJG, 2018, 24(28): 3071-3089. doi: 10.3748/wjg.v24.i28.3071
[10]	帕孜热·赛福丁. 非酒精性脂肪肝与幽门螺杆菌感染的相关性分析[D]. 乌鲁木齐: 新疆医科大学, 2016.
[11]	于晓辉, 马骥, 张久聪, 等. 健康成年人幽门螺杆菌感染特点分析[J]. 西部中医药, 2018, 31(11): 62-64.
[12]	Vaziri F, Tarashi S, Fateh A, et al. New insights of Helicobacter pylori host-pathogen interactions: The triangle of virulence factors, epigenetic modifications and non-coding RNAs[J]. World J Clin Cases, 2018, 6(5): 64-73. doi: 10.12998/wjcc.v6.i5.64
[13]	Sugano K, Tack J, Kuipers E J, et al. Kyoto global consensus report on Helicobacter pylori gastritis[J]. Gut, 2015, 64(9): 1353-1367. doi: 10.1136/gutjnl-2015-309252
[14]	张明磊. 沈阳地区幽门螺杆菌流行病学调查研究[C]. 宁波: 中国微生物学会临床微生物学专业委员会, 2012.
[15]	文婷婷, 陈亚芳, 戴娜, 等. 幽门螺杆菌感染临床检测方法及应用进展[J]. 陕西医学杂志, 2018, 47(12): 1670-1673. https://www.cnki.com.cn/Article/CJFDTOTAL-SXYZ201812045.htm
[16]	唐海灵, 庄坤, 闫媛, 等. 6085例人群中幽门螺杆菌感染的特征分析[J]. 中国卫生检验杂志, 2017, 27(24): 3620-3621.
[17]	Kimura T, Nishikawa T. A biomarker panel: an additional resource in acute stroke evaluation[J]. Minerva Anestesiol, 2013, 79(7): 711-712. http://europepmc.org/abstract/MED/23558768
[18]	Barbieri A, Giuliani E, Carone C, et al. Clinical severity of ischemic stroke and neural damage biomarkers in the acute setting: the stroke markers (STROMA) study[J]. Minerva Anestesiol, 2013, 79(7): 750-757. http://www.ncbi.nlm.nih.gov/pubmed/23511364
[19]	孟清, 陈芹芹, 杨丽君, 等. 幽门螺杆菌感染与2型糖尿病的相关性分析[J]. 世界最新医学信息文摘, 2018, 18(18): 32-33, 39. https://www.cnki.com.cn/Article/CJFDTOTAL-YXXS200820084.htm
[20]	Chongruksut W, Limpakan Yamada S, Chakrabandhu B, et al. Correlation of Helicobacter pylori and interleukin-8 mRNA expression in high risk gastric cancer population prediction[J]. World J Gastrointest Oncol, 2016, 8(2): 215-221. doi: 10.4251/wjgo.v8.i2.215
[21]	朱春英. 幽门螺杆菌感染与糖尿病的相关性[J]. 河北医药, 2017, 39(3): 445-446. https://www.cnki.com.cn/Article/CJFDTOTAL-LCXH202006024.htm
[22]	韩煦. 中老年人群2型糖尿病危险因素识别和发生风险预测模型建立[D]. 武汉: 华中科技大学, 2017.
[23]	Park M J, Choi S H, Kim D, et al. Association between helicobacter pylori seropositivity and the coronary artery calcium score in a screening population[J]. Gut Liver, 2011, 5(3): 321-327. doi: 10.5009/gnl.2011.5.3.321
[24]	Gunji T, Matsuhashi N, Sato H, et al. Helicobacter pylori infection is significantly associated with metabolic syndrome in the Japanese population[J]. Am J Gastroenterol, 2008, 103(12): 3005-3010. doi: 10.1111/j.1572-0241.2008.02151.x
[25]	王少君, 邹德玲, 任丽, 等. 幽门螺杆菌感染对老年急性冠状动脉综合征患者炎性因子、血脂指标和冠状动脉狭窄程度的影响[J]. 疑难病杂志, 2018, 17(10): 1099-1103. doi: 10.3969/j.issn.1671-6450.2018.10.005
[26]	Hosseini A, Salman M, Zhou Z, et al. Level of dietary energy and 2, 4-thiazolidinedione alter molecular and systemic biomarkers of inflammation and liver function in Holstein cows[J]. J Anim Sci Biotechnol, 2017, 8: 64-64. doi: 10.1186/s40104-017-0196-y
[27]	Vanessa K. Ridaura, Jeremiah J. Faith, Federico E. Rey, Jiye Cheng, Alexis E. Duncan. Cultured gut microbiota from twins discordant for obesity modulate adiposity and metabolic phenotypes in mice[J]. Science, 2013, 341(6150): 1241214-1241214. doi: 10.1126/science.1241214
[28]	练卫星, 张义军, 刘忆玲. 门诊受检患者幽门螺杆菌检测中¹³C-尿素呼气试验的应用价值分析[J]. 临床检验杂志: 电子版, 2019, 8(3): 6-6. https://www.cnki.com.cn/Article/CJFDTOTAL-LNJI201903004.htm
[29]	李勋, 蔡英茂, 金仁仙, 等. Kawamura分类法在评价幽门螺杆菌感染和胃炎中的价值[J]. 临床内科杂志, 2019(4): 247-249. doi: 10.3969/j.issn.1001-9057.2019.04.009
[30]	杨林, 康乐斯基, 江华, 等. 阿坝州藏区人群幽门螺杆菌感染流行病学调查及相关影响因素分析[J]. 实用医院临床杂志, 2019, 16(2): 18-20. doi: 10.3969/j.issn.1672-6170.2019.02.006
[31]	张琰, 程艳萍, 杨圣, 等. 南京市鼓楼区中老年居民幽门螺杆菌感染现状及相关因素研究[J]. 中国预防医学杂志, 2019, 20(1): 1-5. https://www.cnki.com.cn/Article/CJFDTOTAL-ZGYC201901003.htm

Cited By

Cited by

Periodical cited type(2)

1.	胡永胜，黄栗，潘玲玲，胡侠. 硒酵母片致尿酸升高1例. 临床合理用药. 2025(04): 164-166 .
2.	李亚星，张俊勤. 局部晚期宫颈癌患者采用恩度配合同步放化疗治疗的效果及对血清指标的影响. 中国医药科学. 2023(22): 171-174 .

Other cited types(0)

Get Citation

PDF

XML

Article views (335) PDF downloads (6) Cited by(2)

Turn off MathJax

Article Contents

Abstract

References

Investigation on infection status of population with Helicobacter pylori infection in Shengyang region

Abstract

References

Cited by

Periodical cited type(2)

Other cited types(0)

Catalog

Export File

Citation

Format

Content