GUO Ying, PEI Dongmei, ZHANG Naisi. Investigation on infection status of population with Helicobacter pylori infection in Shengyang region[J]. Journal of Clinical Medicine in Practice, 2019, 23(13): 99-101, 105. DOI: 10.7619/jcmp.201913028
Citation: GUO Ying, PEI Dongmei, ZHANG Naisi. Investigation on infection status of population with Helicobacter pylori infection in Shengyang region[J]. Journal of Clinical Medicine in Practice, 2019, 23(13): 99-101, 105. DOI: 10.7619/jcmp.201913028

Investigation on infection status of population with Helicobacter pylori infection in Shengyang region

More Information
  • Received Date: May 14, 2019
  • Accepted Date: June 21, 2019
  • Available Online: February 23, 2021
  • Published Date: July 14, 2019
  •   Objective  To investigate the infection status of Helicobacter pylori(Hp) infection in Shenyang region, and to analyze its infection characteristics and related factors.
      Methods  The data of population with Hp infection detected in our physical examination center from January to December 2018 were retrospectively studied. These patients were divided into three groups according to varied ages: the youth group, the middle-aged group and the elderly group, and two groups according to the infection conditions: Hp-positive group and negative group. The characteristics of infections in varied gender and age groups were analyzed, and relationship between Hp infection and blood glucose, blood lipids were observed.
      Results  14C urea exhalation test was carried out in 11 775 people, with total infection rate of 30.99%. In the positive group, there were 2 376 male cases, and 1 273 female cases, with the infection rate of 65.11%, 34.89%, respectively, the differences were statistically significant (P < 0.05). The positive and negative rates of Hp in the young group showed significant differences compared to those in the middle-aged and elderly groups (P < 0.01), but no significant differences were seen between the middle-aged group and the elderly group (P>0.05). The blood glucose, triglyceride and low-density cholesterol levels in Hp-positive group were higher than those in Hp-negative group (P < 0.05), but there was no significant between-group differences in total cholesterol and high-density cholesterol(P>0.05).
      Conclusion  Hp positive infection is related to age, sex, blood glucose, triglyceride and low-density cholesterol, but has no significant correlation with total cholesterol and high-density cholesterol.
  • [1]
    McGuigan A, Kelly P, Turkington R C, et al. Pancreatic cancer: A review of clinical diagnosis, epidemiology, treatment and outcomes[J]. World J Gastroenterol, 2018, 24(43): 4846-4861. doi: 10.3748/wjg.v24.i43.4846
    [2]
    白焕焕. 肠内营养对溃疡性结肠炎患者的疗效评价及生活质量评估[D]. 长春: 吉林大学, 2016.
    [3]
    Khademi F, Poursina F, Hosseini E, et al. Helicobacter pylori in Iran: A systematic review on the antibiotic resistance[J]. Iran J Basic Med Sci, 2015, 18(1): 2-7. http://pubmedcentralcanada.ca/pmcc/articles/PMC4366738/
    [4]
    Flores-Treviño C E, Urrutia-Baca V H, Gómez-Flores R, et al. Molecular detection of Helicobacter pylori based on the presence of cagA and vacA virulence genes in dental plaque from patients with periodontitis[J]. J Dent Sci, 2019, 14(2): 163-170. doi: 10.1016/j.jds.2019.01.010
    [5]
    王欢, 熊梅, 付丽, 等. 2型糖尿病患者颈动脉粥样硬化与幽门螺杆菌感染的相关性研究[J]. 临床和实验医学杂志, 2017, 16(11): 1116-1119. doi: 10.3969/j.issn.1671-4695.2017.11.025
    [6]
    卢学勉. 2型糖尿病患者心脑血管病变和幽门螺杆菌感染之间的关系[C]. 杭州: 浙江省医学会内分泌学分会: 浙江省科学技术协会, 2005.
    [7]
    Zhao Z W, Kang W M, Ma Z Q, et al. Gastric cancer with severe immune thrombocytopenia: A case report[J]. World J Clin Cases, 2018, 6(15): 1024-1028. doi: 10.12998/wjcc.v6.i15.1024
    [8]
    Rahmani Y, Mohammadi S, Babanejad M, et al. Association of helicobacter pylori with presence of myocardial infarction in iran: a systematic review and meta-analysis[J]. Ethiop J Health Sci, 2017, 27(4): 433-440. doi: 10.4314/ejhs.v27i4.15
    [9]
    Bravo D, Hoare A, Soto C, et al. Helicobacter pylori in human health and disease: Mechanisms for local gastric and systemic effects[J]. WJG, 2018, 24(28): 3071-3089. doi: 10.3748/wjg.v24.i28.3071
    [10]
    帕孜热·赛福丁. 非酒精性脂肪肝与幽门螺杆菌感染的相关性分析[D]. 乌鲁木齐: 新疆医科大学, 2016.
    [11]
    于晓辉, 马骥, 张久聪, 等. 健康成年人幽门螺杆菌感染特点分析[J]. 西部中医药, 2018, 31(11): 62-64.
    [12]
    Vaziri F, Tarashi S, Fateh A, et al. New insights of Helicobacter pylori host-pathogen interactions: The triangle of virulence factors, epigenetic modifications and non-coding RNAs[J]. World J Clin Cases, 2018, 6(5): 64-73. doi: 10.12998/wjcc.v6.i5.64
    [13]
    Sugano K, Tack J, Kuipers E J, et al. Kyoto global consensus report on Helicobacter pylori gastritis[J]. Gut, 2015, 64(9): 1353-1367. doi: 10.1136/gutjnl-2015-309252
    [14]
    张明磊. 沈阳地区幽门螺杆菌流行病学调查研究[C]. 宁波: 中国微生物学会临床微生物学专业委员会, 2012.
    [15]
    文婷婷, 陈亚芳, 戴娜, 等. 幽门螺杆菌感染临床检测方法及应用进展[J]. 陕西医学杂志, 2018, 47(12): 1670-1673. https://www.cnki.com.cn/Article/CJFDTOTAL-SXYZ201812045.htm
    [16]
    唐海灵, 庄坤, 闫媛, 等. 6085例人群中幽门螺杆菌感染的特征分析[J]. 中国卫生检验杂志, 2017, 27(24): 3620-3621.
    [17]
    Kimura T, Nishikawa T. A biomarker panel: an additional resource in acute stroke evaluation[J]. Minerva Anestesiol, 2013, 79(7): 711-712. http://europepmc.org/abstract/MED/23558768
    [18]
    Barbieri A, Giuliani E, Carone C, et al. Clinical severity of ischemic stroke and neural damage biomarkers in the acute setting: the stroke markers (STROMA) study[J]. Minerva Anestesiol, 2013, 79(7): 750-757. http://www.ncbi.nlm.nih.gov/pubmed/23511364
    [19]
    孟清, 陈芹芹, 杨丽君, 等. 幽门螺杆菌感染与2型糖尿病的相关性分析[J]. 世界最新医学信息文摘, 2018, 18(18): 32-33, 39. https://www.cnki.com.cn/Article/CJFDTOTAL-YXXS200820084.htm
    [20]
    Chongruksut W, Limpakan Yamada S, Chakrabandhu B, et al. Correlation of Helicobacter pylori and interleukin-8 mRNA expression in high risk gastric cancer population prediction[J]. World J Gastrointest Oncol, 2016, 8(2): 215-221. doi: 10.4251/wjgo.v8.i2.215
    [21]
    朱春英. 幽门螺杆菌感染与糖尿病的相关性[J]. 河北医药, 2017, 39(3): 445-446. https://www.cnki.com.cn/Article/CJFDTOTAL-LCXH202006024.htm
    [22]
    韩煦. 中老年人群2型糖尿病危险因素识别和发生风险预测模型建立[D]. 武汉: 华中科技大学, 2017.
    [23]
    Park M J, Choi S H, Kim D, et al. Association between helicobacter pylori seropositivity and the coronary artery calcium score in a screening population[J]. Gut Liver, 2011, 5(3): 321-327. doi: 10.5009/gnl.2011.5.3.321
    [24]
    Gunji T, Matsuhashi N, Sato H, et al. Helicobacter pylori infection is significantly associated with metabolic syndrome in the Japanese population[J]. Am J Gastroenterol, 2008, 103(12): 3005-3010. doi: 10.1111/j.1572-0241.2008.02151.x
    [25]
    王少君, 邹德玲, 任丽, 等. 幽门螺杆菌感染对老年急性冠状动脉综合征患者炎性因子、血脂指标和冠状动脉狭窄程度的影响[J]. 疑难病杂志, 2018, 17(10): 1099-1103. doi: 10.3969/j.issn.1671-6450.2018.10.005
    [26]
    Hosseini A, Salman M, Zhou Z, et al. Level of dietary energy and 2, 4-thiazolidinedione alter molecular and systemic biomarkers of inflammation and liver function in Holstein cows[J]. J Anim Sci Biotechnol, 2017, 8: 64-64. doi: 10.1186/s40104-017-0196-y
    [27]
    Vanessa K. Ridaura, Jeremiah J. Faith, Federico E. Rey, Jiye Cheng, Alexis E. Duncan. Cultured gut microbiota from twins discordant for obesity modulate adiposity and metabolic phenotypes in mice[J]. Science, 2013, 341(6150): 1241214-1241214. doi: 10.1126/science.1241214
    [28]
    练卫星, 张义军, 刘忆玲. 门诊受检患者幽门螺杆菌检测中13C-尿素呼气试验的应用价值分析[J]. 临床检验杂志: 电子版, 2019, 8(3): 6-6. https://www.cnki.com.cn/Article/CJFDTOTAL-LNJI201903004.htm
    [29]
    李勋, 蔡英茂, 金仁仙, 等. Kawamura分类法在评价幽门螺杆菌感染和胃炎中的价值[J]. 临床内科杂志, 2019(4): 247-249. doi: 10.3969/j.issn.1001-9057.2019.04.009
    [30]
    杨林, 康乐斯基, 江华, 等. 阿坝州藏区人群幽门螺杆菌感染流行病学调查及相关影响因素分析[J]. 实用医院临床杂志, 2019, 16(2): 18-20. doi: 10.3969/j.issn.1672-6170.2019.02.006
    [31]
    张琰, 程艳萍, 杨圣, 等. 南京市鼓楼区中老年居民幽门螺杆菌感染现状及相关因素研究[J]. 中国预防医学杂志, 2019, 20(1): 1-5. https://www.cnki.com.cn/Article/CJFDTOTAL-ZGYC201901003.htm
  • Cited by

    Periodical cited type(25)

    1. 蒋佳玲,杨童玲. 1例持续性肺动脉高压合并母体HIV感染新生儿的多元个性化护理. 全科护理. 2024(24): 4742-4746 .
    2. 王风洋. 不同浓度一氧化氮联合米力农对新生儿胎粪吸入性肺炎持续肺动脉高压患儿肺氧合功能及炎性反应的影响. 中国妇幼保健. 2023(01): 48-51 .
    3. 陈顺何,李霜洁,杨夏敏. 米力农和西地那非分别联合机械通气治疗新生儿PPHN疗效评价. 中国处方药. 2023(01): 103-106 .
    4. 郑碧娟. 米力农联合酚妥拉明对新生儿肺动脉持续高压患儿动脉血气及血清炎症指标的影响. 淮海医药. 2023(04): 407-409 .
    5. 吴旭婷,凌超民,陈晓琳. 呼吸训练器联合床旁端坐法对ICU机械通气患者膈肌功能的影响. 哈尔滨医药. 2022(06): 31-33 .
    6. 刘倩,张爱梅. 高频振荡通气下西地那非联合米力农治疗新生儿持续肺动脉高压的疗效观察. 当代医学. 2021(02): 83-86 .
    7. 谭乐. 米力农联合高频通气对新生儿持续性肺动脉高压患儿血气指标的影响. 当代医学. 2021(03): 138-139 .
    8. 李明耀,陈文滨. 西地那非联合米力农治疗新生儿持续肺动脉高压疗效及对细胞因子表达的影响. 中国处方药. 2021(02): 73-74 .
    9. 王会影,范雪爱,田艳茹,李正川,靳雅玲,刘欣. 一氧化氮吸入联合高频振荡通气治疗新生儿持续性肺动脉高压的效果分析. 中国病案. 2021(01): 96-100 .
    10. 陈尊,刘芳,邓健. 小剂量多巴胺和多巴酚丁胺静脉滴注联合高频振荡通气治疗新生儿持续肺动脉高压的临床疗效研究. 实用心脑肺血管病杂志. 2021(03): 101-105 .
    11. 柳慧. 米力农与硫酸镁单一及联合用药治疗新生儿肺动脉高压的疗效对比. 现代诊断与治疗. 2021(03): 362-363 .
    12. 李海志,王丹,李特. 米力农治疗新生儿持续性肺动脉高压有效性的系统评价. 中国医院用药评价与分析. 2021(03): 324-328 .
    13. 刘欣,何海英,刘利军,吴海焕. 米力农治疗新生儿持续性肺动脉高压的Meta分析. 中国卫生标准管理. 2021(18): 100-103 .
    14. 全守东,于亚杰,梁志霞. 一氧化氮吸入联合米力农治疗新生儿持续性肺动脉高压的疗效及对血流动力学、血小板聚集功能的影响. 临床和实验医学杂志. 2020(01): 89-91 .
    15. 黄杰,乾艾娜,甘斌,何源,魏贤. 米力农对新生儿持续肺动脉高压的治疗作用评价. 中国继续医学教育. 2020(05): 131-133 .
    16. 齐丽娟. 强化护理动脉血气技术对临床诊断治疗的意义探讨. 人人健康. 2020(10): 169 .
    17. 陈波,白波,李广洪,黄学良,罗惠玲,黄惠仪. 波生坦治疗新生儿缺氧性肺动脉高压的临床观察. 中国药房. 2020(10): 1247-1252 .
    18. 蔡云. 高频振荡通气联合多巴胺治疗PPHN的效果及对氧合指数、D-D水平的影响. 数理医药学杂志. 2020(06): 857-859 .
    19. 曹玉晖,南彦武,贾永锋. 米力农和硫酸镁治疗新生儿肺动脉高压的临床效果比较. 临床医学研究与实践. 2020(29): 92-94 .
    20. 曹祎明,胡玉莲,于凤琴,王广州. 米力农联合高频震荡通气治疗新生儿缺氧性肺动脉高压的疗效及对HIF-1α ET-1 HO-1水平的影响. 安徽医学. 2020(11): 1299-1302 .
    21. 吴丹,刘颖,董世霄,翁景文,张金晶,王晓娇,黑明燕,王亚娟. 早产儿与足月儿新生儿持续性肺动脉高压临床资料的对比分析. 北京医学. 2020(12): 1201-1205 .
    22. 马兵. 分析米力农对新生儿持续性肺动脉高压的临床治疗效果. 世界最新医学信息文摘. 2019(25): 54 .
    23. 李华,李泉泉,刘本玉. 米力农对新生儿持续肺动脉高压的疗效. 中国卫生标准管理. 2019(10): 40-42 .
    24. 王彦波,李敏,金宝,王云,陈洋,吴杰斌,刘枭,周彬. 机械通气联合西地那非对新生儿持续性肺动脉高压血流动力学及细胞因子的影响. 中华临床医师杂志(电子版). 2019(09): 659-663 .
    25. 张进军,王瑛,李海欣,张琳,王淮燕. 新生儿窒息复苏后发生持续性肺动脉高压的相关因素及预防措施. 实用临床医药杂志. 2019(20): 32-34+38 . 本站查看

    Other cited types(0)

Catalog

    Article views PDF downloads Cited by(25)

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return