YIN Jianhua, ZHU Jianwei, GU Lichao, ZHONG Yafei, YANG Yao, JIANG Nan, YANG Lijun. Clinical value of early diagnosis in elderly patients with pulmonary embolism[J]. Journal of Clinical Medicine in Practice, 2019, 23(17): 103-106. DOI: 10.7619/jcmp.201917029
Citation: YIN Jianhua, ZHU Jianwei, GU Lichao, ZHONG Yafei, YANG Yao, JIANG Nan, YANG Lijun. Clinical value of early diagnosis in elderly patients with pulmonary embolism[J]. Journal of Clinical Medicine in Practice, 2019, 23(17): 103-106. DOI: 10.7619/jcmp.201917029

Clinical value of early diagnosis in elderly patients with pulmonary embolism

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  • Received Date: June 14, 2019
  • Accepted Date: August 14, 2019
  • Available Online: February 28, 2021
  • Published Date: September 14, 2019
  •   Objective  To investigate the clinical value of early diagnosis in elderly patients with pulmonary embolism.
      Methods  A total of 115 elderly patients with pulmonary embolism who were examined in our hospital were selected as group A, and another 115 non-elderly patients with pulmonary embolism who were examined at the same period were selected as group B. Among them, there were 56 males and 59 females in group A, aged 60 years and above, 57 males and 58 females in group B, aged below 60 years.
      Results  There was no significant difference in the ratio of male to female in group A(48.70%vs. 51.30%) and group B(49.57%vs. 50.43%) (P>0.05). The age, mortality within 30 days, mortality after 30 days, and rate of thrombolytic therapy were (74.31±1.23) years, 21.74%, 42.61%, 9.57%, respectively, in group A, which were significantly higher than (50.38±1.08) years, 10.43%, 13.91%and 3.49%, respectively, in the group B(P < 0.05). There was no significant difference in the incidence of complicating with tumors between group A (11.30%) and group B (12.17%) (P>0.05). The incidences of arrhythmia, pneumonia, cardiac insufficiency, chronic obstructive pulmonary disease, renal insufficiency, hypertension, hypoproteinemia, diabetes and hyperlipidemiain were 31.30%, 33.91%, 36.52%, 26.96%, 37.39%, 65.21%, 18.26%, 32.17%, 16.52%, respectively, in the group A, which were higher than 17.39%, 1.74%, 5.22%, 1.74%, 0.87%, 27.83%, 1.74%, 5.22%, 2.61%, respectively, in group B(P < 0.05)The blood pressure, pulse wave, cardiac troponin I and serum uric acid in group A were significantly higher, and arterial oxygen saturation was significantly lower than that in the control group (P < 0.05). The levels of D-dimer, and serum albumin were (5.89±1.23) mg/L, (24.13±0.23) g/L, respectively, in group A, and were (4.03±0.41) mg/L and (24.09±0.01) g/L, respectively, in group B, which showed no significant differences between two groups.
      Conclusion  Early diagnosis is of high clinical value for elderly patients with pulmonary embolism. The high-risk indicators of early diagnosis can be reference for timely treatment.
  • [1]
    Fan L, Shabbir A, McLure S, et al. Clinical outcomes of clopidogrel versus ticagrelor in the elderly patients with acute coronary syndrome[J]. Heart, 2017, 103(Suppl 5): A52-A52. http://heart.bmj.com/content/103/Suppl_5/A52.2
    [2]
    Jaquet E, Tritschler T, Stalder O, et al. Prediction of short-term prognosis in elderly patients with acute pulmonary embolism: validation of the RIETE score[J]. J Thromb Haemost, 2018, 16(7): 1313-1320. doi: 10.1111/jth.14137
    [3]
    Spence J D. Cuff artifact, J curve, and application of hypertension guidelines in the elderly[J]. Can J Cardiol, 2017, 33(8): 591-593 http://smartsearch.nstl.gov.cn/paper_detail.html?id=e486b0a29350afb1270b4dec82ccbac0
    [4]
    Faller N, Limacher A, Méan M, et al. Predictors and causes of long-term mortality in elderly patients with acute venous thromboembolism: A prospective cohort study[J]. Am J Med, 2017, 130(2): 198-206. doi: 10.1016/j.amjmed.2016.09.008
    [5]
    Engbers M J, Blom J W, Cushman M, et al. Functional impairment and risk of venous thrombosis in older adults[J]. J Am Geriatr Soc, 2017, 65(9): 2003-2008. doi: 10.1111/jgs.14964
    [6]
    Stein P D, Matta F, Hughes M J. Inferior vena cava filters in elderly patients with stable acute pulmonary embolism[J]. Am J Med, 2017, 130(3): 356-364. doi: 10.1016/j.amjmed.2016.09.033
    [7]
    Nathan V, Paul S, Prioleau T, et al. A survey on smart homes for aging in place: toward solutions to the specific needs of the elderly[J]. IEEE Signal Process Mag, 2018, 35(5): 111-119. doi: 10.1109/MSP.2018.2846286
    [8]
    陈央, 周海霞, 胡月红, 等. 老年和非老年肺栓塞的危险因素及Caprini血栓风险评估量表的预测价值[J]. 中华医学杂志, 2017, 97(10): 755-760. doi: 10.3760/cma.j.issn.0376-2491.2017.10.008
    [9]
    贺芬宜, 严赟, 司徒明珠. 超声心动图联合下肢深静脉超声对急性肺栓塞诊断的临床价值研究[J]. 中国超声医学杂志, 2018, 34(12): 1084-1087. doi: 10.3969/j.issn.1002-0101.2018.12.010
    [10]
    杨琼芳, 季巧英, 赵兰艳, 等. 预测CT肺动脉造影联合肺通气灌注显像检查降低肺栓塞复发率的临床价值[J]. 实用医学杂志, 2017, 33(10): 1647-1650. doi: 10.3969/j.issn.1006-5725.2017.10.031
    [11]
    彭晓琼, 王政平. 泌尿外科机器人手术后并发静脉血栓栓塞症的原因分析与护理对策[J]. 中华泌尿外科杂志, 2018, 39(z1): 79-82. doi: 10.3760/cma.j.issn.1000-6702.2018.z1.028
    [12]
    Ma Y X, Wang Y L, Liu D X, et al. A safe strategy to rule out pulmonary embolism: The combination of the Wells score and D-dimer test: One prospective study[J]. Thromb Res, 2017, 156: 160-162. doi: 10.1016/j.thromres.2017.06.018
    [13]
    Goodacre S, Hunt B, Parmar K, et al. 19 Accuracy of biomarkers for venous thromboembolism in pregnancy: the diagnosis of pulmonary embolism in pregnancy (DiPEP) biomarker study[J]. Emerg Med J, 2017, 34(12): A874-A875. doi: 10.1136/emermed-2017-207308.19
    [14]
    Canty D J, Heiberg J, Yang Y, et al. Pilot multi-centre randomised trial of the impact of pre-operative focused cardiac ultrasound on mortality and morbidity in patients having surgery for femoral neck fractures (ECHONOF-2 pilot)[J]. Anaesthesia, 2018, 73(4): 428-437. doi: 10.1111/anae.14130
    [15]
    李成兰, 白彩云, 周玲. 剖宫产术后发生肺栓塞及出血的相关因素及低分子肝素的预防和治疗效果观察[J]. 实用临床医药杂志, 2017, 21(9): 205-206, 214. doi: 10.7619/jcmp.201709068
    [16]
    吴珂. 血压正常伴右心功能不全的急性肺栓塞患者远期预后的危险因素分析[J]. 实用临床医药杂志, 2017, 21(3): 179-180, 187. doi: 10.7619/jcmp.201703061
    [17]
    胡彩霞, 吴霞, 张利敏, 等. 综合护理干预在肺栓塞患者康复治疗中的应用研究[J]. 实用临床医药杂志, 2017, 21(14): 154-155. doi: 10.7619/jcmp.201714048
    [18]
    王巍, 王琼, 郑海宁, 等. 彩色多普勒超声诊断下肢深静脉血栓与肺栓塞的相关性[J]. 临床军医杂志, 2015, 43(11): 835-837. https://www.cnki.com.cn/Article/CJFDTOTAL-JYGZ201511018.htm
    [19]
    韩芳, 安学东, 张伟东. 老年肺部感染患者急性肺栓塞的病原学分析与临床治疗[J]. 中华医院感染学杂志, 2015, 25(14): 3221-3223. https://www.cnki.com.cn/Article/CJFDTOTAL-ZHYY201514039.htm
    [20]
    中华医学会心血管病学分会肺血管病学组. 急性肺血栓栓塞症诊断治疗中国专家共识. 中华内科杂志, 2010, 49(1): 74-81. doi: 10.3760/cma.j.issn.0578-1426.2010.01.026
    [21]
    李杰, 陈殿森, 彭楠. 核医学及分子成像在肺栓塞诊断中的现状及进展[J]. 中国医药导报, 2018, 15(11): 41-44. https://www.cnki.com.cn/Article/CJFDTOTAL-YYCY201811011.htm
    [22]
    韩连丽, 李月峰, 刘思宏, 等. 64排CT肺动脉造影在肺栓塞影像诊断中的应用价值[J]. 内蒙古中医药, 2017, 36(1): 87-88. doi: 10.3969/j.issn.1006-0979.2017.01.086

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