DOU Limin, LI Dongru, WANG Dong, ZHENG Yongke, DONG Xiaoqiao, YU Wenhua, DAI Wei, LI Jie, ZHANG Danglin. Effect of early clearance of bloody cerebrospinal fluid on the prognosis of patients with severe brain injury surgery[J]. Journal of Clinical Medicine in Practice, 2019, 23(18): 61-64. DOI: 10.7619/jcmp.201918018
Citation: DOU Limin, LI Dongru, WANG Dong, ZHENG Yongke, DONG Xiaoqiao, YU Wenhua, DAI Wei, LI Jie, ZHANG Danglin. Effect of early clearance of bloody cerebrospinal fluid on the prognosis of patients with severe brain injury surgery[J]. Journal of Clinical Medicine in Practice, 2019, 23(18): 61-64. DOI: 10.7619/jcmp.201918018

Effect of early clearance of bloody cerebrospinal fluid on the prognosis of patients with severe brain injury surgery

  •   Objective  To investigate effect of early clearance of bloody cerebrospinal fluid on the prognosis of patients with severe brain injury surgery.
      Methods  A total of 70 severe brain injury patients with surgery were selected and divided into two groups. Experimental group (n=40) was treated with sufficient gelatin sponge and cotton sheet to protect the operative field and hematoma cavity. The suction device was used to absorb blood fluid. The cerebrospinal fluid was released by lumbar puncture or lumbar cistern drainage within 3 to 14 days after operation. Control group (n=40) was given routine operation and treatment. After 3 months of follow-up, hospitalization time, hydrocephalus and Glasgow Outcome Score (GOS) were compared between the two groups.
      Results  The hospitalization time in the experimental group was (17.5±4.8) days, which was significantly shorter than (24.9±8.2) days in the control group (P < 0.05). There were 1 case of hydrocephalus in the experimental group and 5 cases of hydrocephalus in the control group, and there was significant difference between two groups (P < 0.05). The GOS score of the experimental group was significantly better than that of the control group (P < 0.05).
      Conclusion  Early clearance of blood cerebrospinal fluid in patients with severe craniocerebral injury can shorten hospitalization time, reduce the occurrence of hydrocephalus and improve the prognosis.
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