Efficiency of bedside flexible bronchoscope supported by high flow oxygen therapy

  Objective  To explore the clinical effect of bedside flexible bronchoscope supported by high flow oxygen therapy.

  Methods  Totally 27 cases with nasal catheter/mask oxygen inhalation were selected as group A and 51 cases with high flow oxygen inhalation were selected as group B. Changes of mean arterial pressure (MAP) and heart rate (HR) before and during operation were analyzed, and the changes of oxygen index p(O₂)/FiO₂ and partial pressure of carbon dioxide p(CO₂) before and after operation were analyzed as well.

  Results  The intra-operative MAP in both groups was higher than that before operation. The ΔMAP in group B was (12.1±4.7) mmHg, while that in group A was (16.3±5.2) mmHg, and there was a significant difference between two groups (P=0.001). The intra-operative HR in both groups was higher than that before operation. The ΔHR in group B was (21.2±11.2) times per minute, and that in group A was (26.7±11.3) per minute, and there was a significant difference between two groups (P=0.045). Postoperative p(O₂)/FiO₂ in both groups was lower than that before operation. The absolute value of Δp(O₂)/FiO₂ in group B was (-9.5±19.5) mmHg, which was lower than (-23.6±12.2) mmHg in group A, and there was a significant difference between two groups (P=0.002). Postoperative p(CO₂) in both groups was higher than that before operation. The Δp(CO₂) in group B was (2.7±4.7) mmHg, which was lower than (5.0±3.0) mmHg in group A, and there was a significant difference between two groups (P=0.02).

  Conclusion  Transnasal high flow oxygen therapy may reduce the variation rates of MAP and HR in patients with bedside flexible bronchoscope, reduce the risk of examination and improve the patient′s tolerance to examination.