Objective To study the value of high-risk human papilloma virus (HR-HPV), squamous cell carcinoma antigen (SCC-Ag) and squamous cell carcinoma associated antigen (SCCA) levels after radical operation of cervical cancer.
Methods A total of 50 patients with cervical cancer were selected as study subjects, and were followed up every 3 months within 1 to 2 years and every 6 months within 2 to 5 years after surgery. During follow-up, HR-HPV, SCC-Ag and SCCA levels of patients were detected, and their value in prediction of recurrence was explored.
Results The positive rates of HR-HPV and SCC-Ag in 5 recurrence patients after operation were significantly higher than those without recurrence (P < 0.05). The positive rate of serum SCCA in recurrence patients was significantly higher than those without recurrence(P < 0.05).
Conclusion The combined detection of HR-HPV, SCC-Ag and SCCA after radical resection of cervical cancer is of great value in assistant diagnosis, curative effect evaluation and prognosis monitoring of cervical cancer.