Advance Search
ZHAO Yuqing, YANG Hong. Effect of oxygen resuscitation at a concentration of 40% on resuscitation, brain injury and oxygen poisoning in asphyxiated neonates[J]. Journal of Clinical Medicine in Practice, 2019, 23(23): 107-109. DOI: 10.7619/jcmp.201923033
Citation: ZHAO Yuqing, YANG Hong. Effect of oxygen resuscitation at a concentration of 40% on resuscitation, brain injury and oxygen poisoning in asphyxiated neonates[J]. Journal of Clinical Medicine in Practice, 2019, 23(23): 107-109. DOI: 10.7619/jcmp.201923033
shu

Effect of oxygen resuscitation at a concentration of 40% on resuscitation, brain injury and oxygen poisoning in asphyxiated neonates

  • 1.

    Department of Obstetrics and Gynecology, Yulin Third Hospital, Yulin, Shaanxi, 719000

  • 2.

    Department of Obstetrics and Gynecology, Xingping People′s Hospital, Xingping, Shaanxi, 713100

More Information
  • Received Date: September 27, 2019
  • Accepted Date: October 29, 2019
  • Available Online: February 28, 2021
  • Published Date: December 14, 2019
    Graphical Abstract
    • Abstract
  •   Objective  To investigate the effect of oxygen resuscitation at a concentration of 40% on resuscitation, brain injury and oxygen poisoning in asphyxiated neonates.
      Methods  The clinical data of 80 asphyxiated newborns admitted to our hospital were retrospectively analyzed. They were divided into air resuscitation group (n=35) and 40% of oxygen concentration group (n=45) according to different oxygen concentrations, given the same other basic resuscitation treatments and nursing, and were transferred to neonatal care unit after resuscitation. The time to first crying, time to establishment of spontaneous breathing and the Apgar score at 1, 5 and 10 min after birth of asphyxiated newborns in the two groups were observed. The success rate of resuscitation, complications such as brain injury and oxygen poisoning were compared between the two groups.
      Results  The success rate of resuscitation was 100.00% in both groups, and there were no deaths. The time to first crying and the time to establishment of spontaneous breathing in 40% of oxygen concentration group were shorter than those in air resuscitation group (P < 0.05). There was no significant difference in Apgar score at 1 min after birth between the two groups (P>0.05). Apgar scores at 5 and 10 min after birth in 40% of oxygen concentration group were (7.72±1.23) and (6.68±1.37) points, respectively, which were significantly higher than (6.68±1.37) and (8.78±0.84) points, respectively, in air resuscitation group(P < 0.05). The Neonatal Behavioral Neurological Assessment (NBNA) score at 2 to 3 days after resuscitation in 40%of oxygen concentration group was higher, and the incidence of brain injury was lower than that of air resuscitation group (P < 0.05). There was no significant difference in the incidence of neonatal oxygen poisoning between the two groups (P>0.05).
      Conclusion  Oxygen resuscitation at a concentration of 40% and air oxygen concentration resuscitation both have satisfactory resuscitation success rate of asphyxiated neonates, but the former has more advantages in improving clinical symptoms of neonatal asphyxia and preventing brain injury, and does not increase complications of oxygen poisoning.
    • FullText(HTML)
    • References (9)
  • [1]
    叶鸿瑁. 为了降低新生儿窒息死亡率的共同目标: 《中华围产医学杂志》与中国新生儿复苏项目合作十余年[J]. 中华围产医学杂志, 2018, 21(4): 221-223. doi: 10.3760/cma.j.issn.1007-9408.2018.04.003
    [2]
    吴琴, 熊丽, 彭勇, 等. 全面二胎政策下的产科安全因素分析及对策的研究[J]. 四川医学, 2018, 39(12): 1408-1412. https://www.cnki.com.cn/Article/CJFDTOTAL-SCYX201812026.htm
    [3]
    Mendler M R, Schwarz S, Hechenrieder L, et al. Successful resuscitation in a model of asphyxia and hemorrhage to test different volume resuscitation strategies. A study in newborn piglets after transition[J]. Front Pediatr, 2018, 20(6): 192-198. http://europepmc.org/articles/PMC6048263/
    [4]
    杨静, 高秀清, 王琳琳. 中等氧浓度复苏足月新生儿窒息的临床护理效果[J]. 实用临床医药杂志, 2017, 21(14): 223-225. https://www.cnki.com.cn/Article/CJFDTOTAL-XYZL201714080.htm
    [5]
    刘丽华, 张强, 曲丽. 四川省某三甲医院新生儿窒息的危险因素分析[J]. 广西医科大学学报, 2019, 36(4): 605-609. https://www.cnki.com.cn/Article/CJFDTOTAL-GXYD201904026.htm
    [6]
    Kunikata T, Morita K, Sakurai H, et al. Status of and problems concerning neonatal resuscitation in Japan in 2015[J]. Pediatr Int, 2017, 59(2): 163-166. doi: 10.1111/ped.13089
    [7]
    刘慧, 赵锦宁, 唐仕芳, 等. 振幅整合脑电图在足月新生儿窒息中的临床应用[J]. 检验医学与临床, 2017, 14(24): 3567-3569. doi: 10.3969/j.issn.1672-9455.2017.24.001
    [8]
    成志, 罗小华, 覃碧芳, 等. 产科与儿科协作规范化复苏在新生儿窒息抢救中的应用效果[J]. 中国妇幼保健, 2018, 33(5): 1093-1096. https://www.cnki.com.cn/Article/CJFDTOTAL-ZFYB201805045.htm
    [9]
    郭建平. 不同起始浓度氧复苏方案对足月新生儿窒息抢救的效果[J]. 临床医学研究与实践, 2018(16): 100-101. https://www.cnki.com.cn/Article/CJFDTOTAL-YLYS201816048.htm
    • Related Articles

  • Cited by

    Periodical cited type(6)

    1. 刘明香，彭灿，吴秋萍，韦松玲. 神经外科重症监护室患者的疼痛管理策略与护理实践. 中华神经外科疾病研究杂志. 2024(05): 54-56 .
    2. 成茜，李正明，杨梦兰，卢婷婷，杨艳. 基于色彩心理学理念的系统化护理模式对蛛网膜下腔出血患者心理状态和生存质量的影响. 中国医药导报. 2023(17): 161-165 .
    3. 赵晓丹. 神经外科术后疼痛管理中应用综合性疼痛护理的效果及对生活质量的影响. 河北医药. 2022(19): 3031-3034 .
    4. 袁青春. 基于健康信念的干预模式联合规范化疼痛管理对腹腔镜胆囊切除术患者的影响观察. 现代诊断与治疗. 2022(24): 3779-3781 .
    5. 程晶晶，赵萍，李莉，卢伟伟，陈丹. 个体化团队护理模式在自发性蛛网膜下腔出血患者中的临床应用. 中国医刊. 2021(04): 458-461 .
    6. 孙可心. 咪达唑仑联合芬太尼对重症蛛网膜下腔出血患者脑代谢的影响. 中国当代医药. 2021(31): 99-102 .

    Other cited types(0)

Catalog

    Get Citation
    PDF
    XML
    Article views (236) PDF downloads (7) Cited by(6)
    Turn off MathJax
    Article Contents
    Abstract
    References

    © 2020 《实用临床医药杂志》编辑部

    Address: 江苏省扬州市江阳中路136号，扬州大学江阳路北校区14号楼201室China Pos: 225009Tel: 0514-87978917、87978989、87978807

    苏公网安备 32100302010246号

    Supported by: Beijing Renhe Information Technology Co., Ltd.   Baidu Analytics

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return