Advance Search
ZHANG Zhanhua, TIAN Feng. Expression of serum cortisol levels in post-stroke depression patients before and after treatment and its correlation with depression[J]. Journal of Clinical Medicine in Practice, 2019, 23(24): 34-36. DOI: 10.7619/jcmp.201924011
Citation: ZHANG Zhanhua, TIAN Feng. Expression of serum cortisol levels in post-stroke depression patients before and after treatment and its correlation with depression[J]. Journal of Clinical Medicine in Practice, 2019, 23(24): 34-36. DOI: 10.7619/jcmp.201924011
shu

Expression of serum cortisol levels in post-stroke depression patients before and after treatment and its correlation with depression

  • 1.

    Pre-hospital Emergency Department, Honghui Hospital Affiliated to Xi′an JiaoTong University, Xi′an, Shaanxi, 710054

  • 2.

    Department of Foot and Ankle Surgery, Honghui Hospital Affiliated to Xi′an JiaoTong University, Xi′an, Shaanxi, 710054

More Information
  • Received Date: October 11, 2019
  • Accepted Date: November 18, 2019
  • Available Online: February 28, 2021
  • Published Date: December 27, 2019
    Graphical Abstract
    • Abstract
  •   Objective  To evaluate the expression of serum cortisol in patients with post-stroke depression before and after treatment, and its correlation with depression.
      Methods  A total of 56 patients with post-stroke depression admitted in our hospital were randomly selected as observation group and another 56 patients without depression in the same period were selected as control group. The serum cortisol level of the two groups was detected, and the correlation between the serum cortisol level and post-stroke depression were explored.
      Results  The levels of serum cortisol expression in the observation group before and after treatment were significantly higher than that in the control group, and Hamilton Depression Scale(HAMD) scores of the observation group after treatment was lower than that in the control group (P < 0.05). Logistic linear regression analysis showed that the serum cortisol level was positively correlated with post-stroke depression.
      Conclusion  The expression of serum cortisol level is closely correlated with the incidence of depression after stroke.
    • FullText(HTML)
    • References (16)
  • [1]
    罗强, 田春艳. 脑卒中患者早期应用抗抑郁药物治疗对提高康复治疗的作用研究[J]. 吉林医学, 2015, 36(15): 3266-3267. doi: 10.3969/j.issn.1004-0412.2015.15.033
    [2]
    王希佳. 脑卒中抑郁与神经功能缺损的相关性研究[J]. 医学综述, 2015, 21(21): 3996-3998. doi: 10.3969/j.issn.1006-2084.2015.21.055
    [3]
    王雨. 血清皮质醇水平与脑卒中后抑郁的相关性及其对治疗的指导意义[J]. 解放军医药杂志, 2015, 27(11): 85-88. doi: 10.3969/j.issn.2095-140X.2015.11.023
    [4]
    中华医学会神经病学分会. 中国急性缺血性脑卒中诊治指南2014[J]. 中华神经科杂志, 2015, 48(4): 246-257. doi: 10.3760/cma.j.issn.1006-7876.2015.04.002
    [5]
    孙振晓, 刘化学, 焦林瑛, 等. 医院焦虑抑郁量表的信度及效度研究[J]. 中华临床医师杂志: 电子版, 2017, 11(2): 198-201. doi: 10.3877/cma.j.issn.1674-0785.2017.02.005
    [6]
    姜天梦. 个体化健康教育对子宫瘢痕妊娠患者的影响[J]. 实用中西医结合临床, 2019, 19(9): 160-162. https://www.cnki.com.cn/Article/CJFDTOTAL-SZXL201909082.htm
    [7]
    李莹, 李光校. 中国脑卒中患者抑郁患病率meta分析[J]. 中国公共卫生, 2015, 31(7): 968-972. https://www.cnki.com.cn/Article/CJFDTOTAL-ZGGW201507033.htm
    [8]
    刘添, 余练. 氟哌噻吨美利曲辛配合帕罗西汀治疗脑卒中后抑郁的疗效观察[J]. 齐齐哈尔医学院学报, 2019, 40(12): 1489-1490. doi: 10.3969/j.issn.1002-1256.2019.12.016
    [9]
    楚丽萍, 张亚丽, 郭静, 等. 2型糖尿病并发脑卒中患者抑郁及影响因素分析[J]. 预防医学, 2019, 31(6): 586-588, 592. https://www.cnki.com.cn/Article/CJFDTOTAL-ZYFX201906011.htm
    [10]
    李小明, 胡爱虹, 顾群. 帕罗西汀和盐酸舍曲林治疗脑卒中后抑郁的临床疗效及安全性评价[J]. 中国临床药理学杂志, 2015, 31(10): 815-817. https://www.cnki.com.cn/Article/CJFDTOTAL-GLYZ201510015.htm
    [11]
    叶文辉. 盐酸帕罗西汀治疗抑郁症的效果及不良反应观察[J]. 中外医学研究, 2019, 17(25): 138-140. https://www.cnki.com.cn/Article/CJFDTOTAL-YJZY201925059.htm
    [12]
    张德龙, 饶燕, 廖院平. 宁心安神法联合盐酸舍曲林分散片对抑郁症患者睡眠质量的影响[J]. 江西中医药大学学报, 2019, 31(4): 53-54, 68. https://www.cnki.com.cn/Article/CJFDTOTAL-XYXB201904018.htm
    [13]
    官国东, 陈敬毅, 宁为民. hs-CRP、补体C3、PA及皮质醇水平在脑卒中患者疾病进展中的变化[J]. 海南医学, 2016, 27(9): 1406-1409. doi: 10.3969/j.issn.1003-6350.2016.09.011
    [14]
    邓瑰丽. 急性缺血性脑卒中患者血清超敏C反应蛋白水平变化及其临床意义[J]. 中外医学研究, 2018, 16(25): 172-173. https://www.cnki.com.cn/Article/CJFDTOTAL-YJZY201825083.htm
    [15]
    温友禄, 张新普, 徐海燕, 等. 抑郁症患者中医体质类型与皮质醇水平的关系[J]. 现代医院, 2018, 18(7): 1049-1051. doi: 10.3969/j.issn.1671-332X.2018.07.037
    [16]
    刘晓丹, 王颖, 黄力. 首发重性抑郁障碍患者大脑皮层厚度与血浆皮质醇水平的相关性研究[J]. 临床放射学杂志, 2015, 34(11): 1710-1714. https://www.cnki.com.cn/Article/CJFDTOTAL-LCFS201511002.htm
    • Related Articles

  • Cited by

    Periodical cited type(1)

    1. 郭英惠，代红燕，姚雪萍，任芳，尹娜，左晓婷. Klotho蛋白对大鼠心肌缺血-再灌注损伤的作用机制探究. 现代生物医学进展. 2024(19): 3616-3618+3644 .

    Other cited types(0)

Catalog

    Get Citation
    PDF
    XML
    Article views (399) PDF downloads (10) Cited by(1)
    Turn off MathJax
    Article Contents
    Abstract
    References

    © 2020 《实用临床医药杂志》编辑部

    Address: 江苏省扬州市江阳中路136号，扬州大学江阳路北校区14号楼201室China Pos: 225009Tel: 0514-87978917、87978989、87978807

    苏公网安备 32100302010246号

    Supported by: Beijing Renhe Information Technology Co., Ltd.   Baidu Analytics

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return