WANG Jing, ZHANG Xiaodan, ZHANG Miao, ZHANG Junqiang. Effect observation of continuous block with catheterization in the anterior space of epidural space combined with lumbar low temperature plasma ablation in treatment of patients with discogenic low back pain[J]. Journal of Clinical Medicine in Practice, 2020, 24(5): 36-39. DOI: 10.7619/jcmp.202005010
Citation: WANG Jing, ZHANG Xiaodan, ZHANG Miao, ZHANG Junqiang. Effect observation of continuous block with catheterization in the anterior space of epidural space combined with lumbar low temperature plasma ablation in treatment of patients with discogenic low back pain[J]. Journal of Clinical Medicine in Practice, 2020, 24(5): 36-39. DOI: 10.7619/jcmp.202005010

Effect observation of continuous block with catheterization in the anterior space of epidural space combined with lumbar low temperature plasma ablation in treatment of patients with discogenic low back pain

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  • Received Date: December 05, 2019
  • Available Online: August 26, 2020
  • Objective To investigate the clinical effect of continuous block with catheterization in the anterior space of epidural space combined with lumbar low temperature plasma ablation in treatment of patients with discogenic low back pain. Methods A total of 106 patients with discogenic low back pain were selected and divided into two groups according to the treatment plan. The control group was treated with continuous block with catheterization in the anterior space of epidural space, while the observation group was treated with continuous block with catheterization in the anterior space of epidural space combined with lumbar low temperature plasma ablation. The NRS scores(before operation, 1 week after operation, 1 month after operation, 3 months after operation), the modified Macnab scores(before operation, 1 month after operation, 3 months after operation), the M-JOA scores(before operation, 1 month after operation, 3 months after operation)and the levels of interleukin-1(IL-1)and interleukin-6(IL-6)(before operation, 1 month after operation, 3 months after operation)were compared between the two groups. Results There were no significant difference in NRS scores between the two groups before operation and 1 week after operation(P>0.05). The NRS scores of the observation group were significantly lower than those of the control group at 1 and 3 months after operation(P<0.05). The excellent and good rates of Macnab in the observation group - were significantly higher than those in the control group at 1 and 3 months after operation(P<0.05). At 1 and 3 months after operation, the M-JOA scores of the observation group were significantly higher than those of the control group(P<0.05). The serum levels of IL-1 and IL-6 in the observation group were significantly lower than those in the control group(P<0.05). Conclusion Continuous block with catheterization in the anterior space of epidural space combined with lumbar low temperature plasma ablation is effective and safe in treatment of patients with discogenic low back pain, which can reduce serum IL-1 and IL-6 levels.
  • Saqib M, Bhatti S N, Khan M A, et al. Outcome analysis of two different injection solutions for epidural injection in radicular lumbar backache syndromes[J]. J Ayub Med Coll Abbottabad, 2016, 28(4): 709-714.
    曹春风, 王群波, 卢旻鹏, 等. 椎间盘源性腰痛的诊断和治疗进展[J]. 颈腰痛杂志, 2016, 37(2): 143-146.
    王永铭. 疏肝补肾汤配合运动疗法治疗椎间盘源性腰痛疗效及对生存质量的影响[J]. 现代中西医结合杂志, 2016, 25(22): 2414-2417.
    吴迪, 黄岩石, 郑铁牛, 等. PTED和低温等离子射频治疗椎间盘源性腰痛临床研究[J]. 临床心身疾病杂志, 2018, 24(1): 64-66

    , 83.
    吴照鹏, 马航. 低温等离子靶点消融术联合臭氧治疗盘源性腰痛的临床效果[J]. 临床医学研究与实践, 2019(9): 73-75.
    程秋平, 刘晓瑜, 谢慰, 等. 温针灸结合体位调整护理法治疗椎间盘源性下腰痛临床观察[J]. 中国中医急症, 2016, 25(9): 1749-1752.
    范少勇, 胡梁深, 周明. 中药熏蒸联合洪都督脉经手法治疗椎间盘源性腰痛疗效观察[J]. 广州中医药大学学报, 2019, 36(6): 824-826.
    郭玉娜, 窦智, 李小琳, 等. 低温等离子消融术联合硬膜外置管治疗盘源性腰痛的效果[J]. 中国医药导报, 2018, 15(28): 111-114.
    左明明, 陈雪飘, 刘金锋. 硬膜外腔药物注射治疗腰椎间盘突出症的研究进展[J]. 中国疼痛医学杂志, 2017, 23(4): 299-302.
    Navone S E, Marfia G, Giannoni A, et al. Inflammatory mediators and signalling pathways controlling intervertebral disc degeneration[J]. Histol Histopathol, 2017, 32(6): 523-542.
    芦海燕, 杨立强, 唐元章, 等. 腰椎间盘低温等离子消融联合腰交感神经导管置入治疗盘源性内脏痛的效果[J]. 中国医药导报, 2018, 15(28): 99-102.
    云晨, 韩广, 蒋显锋, 等. 射频消融治疗脊柱内镜术后椎间盘源性脊神经后支疼痛的疗效分析[J]. 中国中西医结合急救杂志, 2018, 25(6): 646-649.
    田鑫, 刘志军, 常峥. 荣筋活血汤联合射频髓核消融术治疗盘源性腰痛的临床观察[J]. 山东中医杂志, 2016, 35(7): 618-620.
    常有军, 邱恒, 马天洪. 身痛逐瘀汤对大鼠变性腰椎间盘内TNF-α、IL-1α、IL-6、MMP-3的影响[J]. 西部医学, 2017, 29(8): 1046-1050.
    杨剑, 康建平, 冯大雄, 等. IL-1和IL-6的表达增强且与盘源性下腰痛改良日本骨科学会(mJOA)评分负相关[J]. 细胞与分子免疫学杂志, 2016, 32(1): 88-91.
    刘剑, 黄昌林, 常祺, 等. 0期诊断技术对军事训练所致椎间盘源性下腰痛患者血清IL-1β, 6-keto-PGF1α及TNF-α水平的影响及其意义[J]. 现代生物医学进展, 2017, 17(9): 1753-1757.
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