ZHOU Zongbin, ZHAO Guifen, LAN Wenquan, LI Yuanfa, ZHOU Zhigang. Analysis of influencing factors of cancer-related anemia in digestive tract tumor patients[J]. Journal of Clinical Medicine in Practice, 2020, 24(8): 63-65. DOI: 10.7619/jcmp.202008016
Citation: ZHOU Zongbin, ZHAO Guifen, LAN Wenquan, LI Yuanfa, ZHOU Zhigang. Analysis of influencing factors of cancer-related anemia in digestive tract tumor patients[J]. Journal of Clinical Medicine in Practice, 2020, 24(8): 63-65. DOI: 10.7619/jcmp.202008016

Analysis of influencing factors of cancer-related anemia in digestive tract tumor patients

More Information
  • Received Date: December 19, 2019
  • Objective To investigate influencing factors of cancer-related anemia in digestive tract tumor patients. Methods A total of 200 digestive tract tumor patients were selected as the research objects, and the occurrence of cancer-related anemia was analyzed. The influencing factors affecting cancer-related anemia were analyzed by univariate analysis, and risk factors were analyzed by Logistic multivariate regression analysis. Results Out of 200 patients with digestive tract tumors, 124 cases had cancer-related anemia(62.00%), including 32 mild cases, 64 moderate cases, 16 severe cases and 12 extremely severe cases. Univariate analysis showed that there were no significant differences in gender, body mass index, smoking, alcohol drinking and complicating with basic diseases between the two groups(P>0.05); there were significant differences in age, TNM stage, Karnofsky Performance Status(KPS)score, hypoproteinemia and antineoplastic treatment between the two groups(P<0.05). Logistic multivariate regression analysis showed that patients aged over 60 years, at stage of Ⅲ or Ⅳ, with KPS scoring>60, hypoproteinemia and antineoplastic therapy were risk factors for cancer-related anemia. Conclusion The incidence of cancer-related anemia in digestive tract is relatively high, occurring mainly in mild to moderate patients. Over 60 years of age, Ⅲ or Ⅳ staging in TNM stage, KPS scoring over 60, hypoproteinemia and anti-cancer treatment are risk factors for cancer-related anemia.
  • Walker M S, Pohl G M, Houts A C, et al. Analysis of the psychological impact of cancer-related symptoms on patients with non-small cell lung cancer[J]. Psycho-Oncology, 2017, 26(6): 755-762.
    Finkelstein F O, Nooten F V, Wiklund I, et al. Measurement properties of the Short Form-36(SF-36)and the Functional Assessment of Cancer Therapy-Anemia(FACT-An)in patients with anemia associated with chronic kidney disease[J]. Health & Quality of Life Outcomes, 2018, 16(1): 111.
    赵琴. 癌性贫血对肿瘤患者生活质量的影响[J]. 临床护理杂志, 2017, 21(1): 63-65.
    宋志刚, 汪济东, 孙琦, 等. 结直肠癌相关性贫血的机制及治疗[J]. 现代仪器与医疗, 2017, 23(5): 68-70.
    刘昊. 贫血与肺癌患者预后的相关性[J]. 肿瘤研究与临床, 2017, 29(7): 463.
    孙婷婷, 张晓晔. 155例肿瘤患者癌性贫血的相关因素分析[J]. 现代肿瘤医学, 2016, 24(5): 782-786.
    杨环, 张宜琪, 王凯, 等. 胃肠道肿瘤合并癌性贫血患者外周血铁调素水平、白细胞介素-6、IFN-γ及TNF-α的浓度变化[J]. 实用癌症杂志, 2016, 31(12): 1933-1935.
    程旭, 陆晔, 李蓉, 等. 铁调素调节蛋白、骨形成蛋白6及铁调素在乳腺癌组织中的表达及其与贫血的关系[J]. 医学研究杂志, 2017, 46(11): 149-152.
    叶秀萍, 黄珍珍, 洪小芳. 宫颈癌中重度贫血患者围手术期的护理及预防对策[J]. 护士进修杂志, 2018, 33(20): 66-68.
    陆志萍, 周扬. 以贫血为首发症状的胃癌患者的临床病理特征与预后分析[J]. 医学理论与实践, 2017, 30(17): 2510-2512.
    王博, 陈焕伟, 吕学文, 等. 贫血与晚期宫颈癌化疗疗效的相关性[J]. 现代肿瘤医学, 2018, 26(2): 285-288.
    马继利. 重组人促红细胞生成素对胃癌相关性贫血患者治疗效果的影响[J]. 医疗装备, 2017, 30(10): 117-118.
    王雪冰, 李康. 自拟生血方加减治疗非小细胞肺癌相关性贫血临床疗效观察[J]. 中华中医药学刊, 2017, 13(9): 2401-2403.
    莫淑婵, 田甜, 吴钟彪. 升血汤对转移性结直肠癌化疗患者免疫功能及相关性贫血的影响[J]. 中医药导报, 2018, 12(1): 70-72.
    杨斌, 张建武. 酶联免疫吸附法测定肿瘤性贫血患者的血清细胞因子水平及其发病机制研究[J]. 中国临床药理学杂志, 2017, 33(12): 1102-1105.
    王希, 夏冰, 张翼鷟. 肿瘤相关性贫血研究进展[J]. 中国肿瘤临床, 2018, 45(14): 759-762.
    魏佳宁, 王凤, 卢蕻迪, 等. 149例老年患者肿瘤相关性贫血的临床分析[J]. 中国实验诊断学, 2018, 22(5): 109-111.
    邱春凤. 重组人红细胞生成素对恶性肿瘤患者贫血及睡眠的影响[J]. 世界睡眠医学杂志, 2017, 4(6): 352-354.
    陈慧莉, 师文静, 姜飞. 晚期恶性肿瘤相关缺铁性贫血调查及静脉铁剂治疗观察[J]. 中国继续医学教育, 2018, 10(14): 143-145.
    陆秋云, 唐华英, 黄迎春, 等. 支持性护理干预联合Orem自理模式对妇科恶性肿瘤病人癌性贫血及生活质量的影响[J]. 护理研究, 2018, 32(16): 96-100.
  • Cited by

    Periodical cited type(25)

    1. 蒋佳玲,杨童玲. 1例持续性肺动脉高压合并母体HIV感染新生儿的多元个性化护理. 全科护理. 2024(24): 4742-4746 .
    2. 王风洋. 不同浓度一氧化氮联合米力农对新生儿胎粪吸入性肺炎持续肺动脉高压患儿肺氧合功能及炎性反应的影响. 中国妇幼保健. 2023(01): 48-51 .
    3. 陈顺何,李霜洁,杨夏敏. 米力农和西地那非分别联合机械通气治疗新生儿PPHN疗效评价. 中国处方药. 2023(01): 103-106 .
    4. 郑碧娟. 米力农联合酚妥拉明对新生儿肺动脉持续高压患儿动脉血气及血清炎症指标的影响. 淮海医药. 2023(04): 407-409 .
    5. 吴旭婷,凌超民,陈晓琳. 呼吸训练器联合床旁端坐法对ICU机械通气患者膈肌功能的影响. 哈尔滨医药. 2022(06): 31-33 .
    6. 刘倩,张爱梅. 高频振荡通气下西地那非联合米力农治疗新生儿持续肺动脉高压的疗效观察. 当代医学. 2021(02): 83-86 .
    7. 谭乐. 米力农联合高频通气对新生儿持续性肺动脉高压患儿血气指标的影响. 当代医学. 2021(03): 138-139 .
    8. 李明耀,陈文滨. 西地那非联合米力农治疗新生儿持续肺动脉高压疗效及对细胞因子表达的影响. 中国处方药. 2021(02): 73-74 .
    9. 王会影,范雪爱,田艳茹,李正川,靳雅玲,刘欣. 一氧化氮吸入联合高频振荡通气治疗新生儿持续性肺动脉高压的效果分析. 中国病案. 2021(01): 96-100 .
    10. 陈尊,刘芳,邓健. 小剂量多巴胺和多巴酚丁胺静脉滴注联合高频振荡通气治疗新生儿持续肺动脉高压的临床疗效研究. 实用心脑肺血管病杂志. 2021(03): 101-105 .
    11. 柳慧. 米力农与硫酸镁单一及联合用药治疗新生儿肺动脉高压的疗效对比. 现代诊断与治疗. 2021(03): 362-363 .
    12. 李海志,王丹,李特. 米力农治疗新生儿持续性肺动脉高压有效性的系统评价. 中国医院用药评价与分析. 2021(03): 324-328 .
    13. 刘欣,何海英,刘利军,吴海焕. 米力农治疗新生儿持续性肺动脉高压的Meta分析. 中国卫生标准管理. 2021(18): 100-103 .
    14. 全守东,于亚杰,梁志霞. 一氧化氮吸入联合米力农治疗新生儿持续性肺动脉高压的疗效及对血流动力学、血小板聚集功能的影响. 临床和实验医学杂志. 2020(01): 89-91 .
    15. 黄杰,乾艾娜,甘斌,何源,魏贤. 米力农对新生儿持续肺动脉高压的治疗作用评价. 中国继续医学教育. 2020(05): 131-133 .
    16. 齐丽娟. 强化护理动脉血气技术对临床诊断治疗的意义探讨. 人人健康. 2020(10): 169 .
    17. 陈波,白波,李广洪,黄学良,罗惠玲,黄惠仪. 波生坦治疗新生儿缺氧性肺动脉高压的临床观察. 中国药房. 2020(10): 1247-1252 .
    18. 蔡云. 高频振荡通气联合多巴胺治疗PPHN的效果及对氧合指数、D-D水平的影响. 数理医药学杂志. 2020(06): 857-859 .
    19. 曹玉晖,南彦武,贾永锋. 米力农和硫酸镁治疗新生儿肺动脉高压的临床效果比较. 临床医学研究与实践. 2020(29): 92-94 .
    20. 曹祎明,胡玉莲,于凤琴,王广州. 米力农联合高频震荡通气治疗新生儿缺氧性肺动脉高压的疗效及对HIF-1α ET-1 HO-1水平的影响. 安徽医学. 2020(11): 1299-1302 .
    21. 吴丹,刘颖,董世霄,翁景文,张金晶,王晓娇,黑明燕,王亚娟. 早产儿与足月儿新生儿持续性肺动脉高压临床资料的对比分析. 北京医学. 2020(12): 1201-1205 .
    22. 马兵. 分析米力农对新生儿持续性肺动脉高压的临床治疗效果. 世界最新医学信息文摘. 2019(25): 54 .
    23. 李华,李泉泉,刘本玉. 米力农对新生儿持续肺动脉高压的疗效. 中国卫生标准管理. 2019(10): 40-42 .
    24. 王彦波,李敏,金宝,王云,陈洋,吴杰斌,刘枭,周彬. 机械通气联合西地那非对新生儿持续性肺动脉高压血流动力学及细胞因子的影响. 中华临床医师杂志(电子版). 2019(09): 659-663 .
    25. 张进军,王瑛,李海欣,张琳,王淮燕. 新生儿窒息复苏后发生持续性肺动脉高压的相关因素及预防措施. 实用临床医药杂志. 2019(20): 32-34+38 . 本站查看

    Other cited types(0)

Catalog

    Article views (462) PDF downloads (7) Cited by(25)

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return