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HU Xiaoyu, WU Yingen. Clinical Observation of Wenyang Kanghan Decoction combined with western medicines in treatment of patients with acute exacerbation of chronic bronchitis[J]. Journal of Clinical Medicine in Practice, 2021, 25(1): 58-61. DOI: 10.7619/jcmp.20200864
Citation: HU Xiaoyu, WU Yingen. Clinical Observation of Wenyang Kanghan Decoction combined with western medicines in treatment of patients with acute exacerbation of chronic bronchitis[J]. Journal of Clinical Medicine in Practice, 2021, 25(1): 58-61. DOI: 10.7619/jcmp.20200864
shu

Clinical Observation of Wenyang Kanghan Decoction combined with western medicines in treatment of patients with acute exacerbation of chronic bronchitis

  • 1.

    Department of Internal Medicine, Shanghai Changning District Tianshan Hospital of Traditional Chinese Medicine, Shanghai, 200051

  • 2.

    Department of Pulmonary Disease, Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, 200032

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  • Received Date: September 17, 2020
  • Available Online: January 17, 2021
  • Published Date: January 14, 2021
    Graphical Abstract
    • Abstract
  • Objective To explore the effect of Wenyang Kanghan Decoction combined with western medicine in treatment of patients with acute exacerbation of chronic bronchitis. Methods A total of 114 patients with acute onset of chronic bronchitis were randomly divided into control group (n=59) and observation group (n=55). The control group was given conventional western medicine treatment, and the treatment group was given Wenyang Kanghan Decoction on the basis of the control group. Clinical efficacy, TCM syndrome score and Leicester cough questionnaire (LCQ) score were compared in the two groups, and the changes of interleukin-2 receptor (IL-2R), interleukin-6 (IL-6), interleukin-8 (IL-8) and interleukin-10 (IL-10) levels in the two groups were analyzed. Results The total effective rate in the treatment group was 90.91%, which significantly higher than 86.44% in the control group (P< 0.05). After treatment, TCM syndrome score and IL-2R, IL-6 and IL-8 levels in the treatment group were significantly lower than those in the control group (P< 0.05); the social, psychological and physiological scores as well as LCQ total score of the treatment group were significantly higher than those of the control group (P< 0.05). Conclusion Wenyang Kanghan Decoction combined with western medicine has a better effect in patients with acute exacerbation of chronic bronchitis differentiated as kidney-yang deficiency syndrome, which can improve the immune level of patients and enhance the quality of life.
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    • References (17)
  • [1]
    胡洁玲, 张天灵, 吴帆等. 祛风散寒法治疗风寒束肺型慢性支气管炎急性发作期的临床疗效观察[J]. 中国现代药物应用, 2017, 11(22): 179-181. https://www.cnki.com.cn/Article/CJFDTOTAL-ZWYY201722106.htm
    [2]
    田伟, 张淑香, 江柏华. 清肺止咳灵糖浆对慢性支气管炎急性发作期大鼠肺组织病理学及血清IL-8、TNF-α的影响[J]. 上海市中医药杂志, 2016, 50(11): 78-81. https://www.cnki.com.cn/Article/CJFDTOTAL-SHZZ201611024.htm
    [3]
    吴银根. 吴银根学术经验撷英[M]. 上海中医药大学出版社, 2009: 138-139.
    [4]
    葛均波, 徐永健, 王辰. 内科学[M]. 第9版. 人民卫生出版社, 2018: 19-21.
    [5]
    郑筱萸. 中药新药临床研究指导原则[M]. 北京: 中国医药科技出版社, 2002, 36(4): 54-58.
    [6]
    BIRRING SS, PRUDON B, CARRAJ, et al. Development of a symptom specific health status measure for patients with chronic cough: Leicester Cough Questionnaire(LCQ)[J]. Thorax, 2003, 58(4): 339-343. doi: 10.1136/thorax.58.4.339
    [7]
    朱可辉. 胸腺肽联合抗生素治疗老年慢性支气管炎急性发作期疗效观察[J]. 现代中西医结合杂志, 2014, 23(13): 1440-1442. doi: 10.3969/j.issn.1008-8849.2014.13.032
    [8]
    费玲, 赵秋良, 张维维. 疏风解毒胶囊对风热犯肺型慢性支气管炎急性发作患者的影响[J]. 世界中医药, 2020, 15(22): 3439-3442. doi: 10.3969/j.issn.1673-7202.2020.22.014
    [9]
    吕元文, 宗文九, 范国荣, 等. 慢性支气管炎及肺癌患者血清可溶性白细胞介素-2受体测定的意义. 临床内科杂志, 1997, 14(2): 78.
    [10]
    莫冠文. 老年慢性支气管炎急性期患者治疗前后血清炎性因子水平变化[J]. 临床合理用药, 2020, 13(7A): 98-99. https://www.cnki.com.cn/Article/CJFDTOTAL-PLHY202019046.htm
    [11]
    陈国超. 小青龙汤合三子养亲汤对慢性支气管炎患者呼吸功能及血清IL-8、CRP水平的影响[J]. 亚太传统医药, 2017, 13(15): 139-140. doi: 10.11954/ytctyy.201715061
    [12]
    陶建峰, 唐斌擎, 方泓等. 咳喘六味中药方联合艾灸治疗寒饮束肺型顽固性感染后咳嗽的临床观察[J]. 上海市中医药杂志, 2013, 47(11): 33-35. https://www.cnki.com.cn/Article/CJFDTOTAL-SHZZ201311016.htm
    [13]
    李少滨, 方泓. 温阳抗寒汤治疗支气管哮喘68例临床观察[J]. 中医临床研究, 2015, 7(36): 28-29. doi: 10.3969/j.issn.1674-7860.2015.36.012
    [14]
    邓嘉, 王导新, 梁爱玲. 黄芩苷胶囊治疗医院获得性肺炎的临床观察[J]. 临床医药实践, 2017, 26(6): 423-427. https://www.cnki.com.cn/Article/CJFDTOTAL-SXLC201706008.htm
    [15]
    杨明, 刘清泉, 周爱国. 清肺止咳化痰汤联合盐酸氨溴索雾化吸入治疗老年慢性支气管炎急性发作疗效观察[J]. 河南中医, 2018, 38(8): 1205-1208. https://www.cnki.com.cn/Article/CJFDTOTAL-HNZY201808019.htm
    [16]
    洪世海, 刘冰冰, 甘国兴. 麻黄汤合百合固金汤化裁治疗慢性支气管炎机制研究[J]. 光明中医, 2014, 29(6): 1188-1190. doi: 10.3969/j.issn.1003-8914.2014.06.034
    [17]
    景菲菲. 射干麻黄汤对老年慢性支气管炎急性发作患者的疗效及其血清炎症因子水平的影响[J]. 河南医学研究, 2020, 29(5): 894-895. doi: 10.3969/j.issn.1004-437X.2020.05.064
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