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XU Qian, CHI Shanshan, HAO Dandan, CHEN Chunyan, LIU Juan. Analysis on high frequency oscillation ventilation combined with pulmonary surfactant in treatment of neonatal meconium aspiration syndrome[J]. Journal of Clinical Medicine in Practice, 2020, 24(14): 60-62,66. DOI: 10.7619/jcmp.202014016
Citation: XU Qian, CHI Shanshan, HAO Dandan, CHEN Chunyan, LIU Juan. Analysis on high frequency oscillation ventilation combined with pulmonary surfactant in treatment of neonatal meconium aspiration syndrome[J]. Journal of Clinical Medicine in Practice, 2020, 24(14): 60-62,66. DOI: 10.7619/jcmp.202014016
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Analysis on high frequency oscillation ventilation combined with pulmonary surfactant in treatment of neonatal meconium aspiration syndrome

  • 1. Department of Neonate, 521 Hospital of Ordnance Industry, Xi'an, Shaanxi, 710065;

  • 2. Department of Pediatrics, Tangdu Hospital of Air Force Military Medical University of People's Liberation Army, Xi'an, Shaanxi, 710038

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  • Received Date: May 10, 2020
    Graphical Abstract
    • Abstract
  • Objective To observe the curative effects of high frequency oscillation ventilation combined with pulmonary surfactant in neonatal meconium aspiration syndrome. Methods The clinical data of 59 neonates with meconium aspiration syndrome was retrospectively analyzed. They were divided into observation group(high frequency oscillation ventilation combined with pulmonary surfactant based on routine treatment, n=33)and control group(high frequency oscillation ventilation based on routine treatment, n=26)according to different treatment methods. The changes of oxygenation indexes before and after treatment, improvement time of clinical indexes after treatment, and incidence of complications were compared between two groups. Results After treatment, the partial pressure of carbon dioxide in arterial blood ［pa(CO2)］, oxygenation index(OI)and fraction of inspiration oxygen(FiO2)in two groups were significantly lower than those before treatment, the partial pressure of oxygen in arterial blood［pa(O2)］ was significantly higher than that before treatment, the pa(CO2), OI and FiO2 in the observation group were significantly lower than those in control group, and the level of pa(O2)in the observation group was significantly higher than that in control group(P<0.05); the ventilator treatment time and hospitalization time in the observation group were shorter - than those in the control group(P<0.05); the incidence of complications in the observation group was lower than that in control group(P<0.05). Conclusion High frequency oscillation ventilation combined with pulmonary surfactant in neonatal meconium aspiration syndrome can effectively improve oxygenation index, shorten hospital stays, decrease the incidence of complications, and increase curative effects.
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  • 王兆康. 高频振荡通气联合猪肺磷脂治疗新生儿重症胎粪吸入综合征合并肺出血的临床效果[J]. 广西医学, 2019, 41(10): 1246-1250.
    黄静, 林新祝. 新生儿胎粪吸入综合征并发肺出血的临床特征及预后分析[J]. 中国当代儿科杂志, 2019, 21(11): 1059-1063.[3] 黄静, 林新祝, 郑直. 高频振荡通气联合肺表面活性物质治疗新生儿重型胎粪吸入综合征并发肺出血的临床研究[J]. 中国当代儿科杂志, 2016, 18(11): 1075-1079.
    邵肖梅, 叶鸿瑁, 丘小汕. 实用新生儿学[M]. 4版. 北京: 人民卫生出版社, 2011: 398-401.
    肖秀漫, 杨祖钦, 黄玉梅, 等. 新生儿胎粪吸入综合征合并良性气腹一例[J]. 中国新生儿科杂志, 2016, 31(6): 467-468.
    曹亚芹, 董玉斌, 张艳华, 等. 高频振荡通气治疗新生儿胎粪吸入综合症临床疗效分析[J]. 临床肺科杂志, 2018, 23(1): 175-177.
    韩娟. 肺表面活性物质联合高频震荡通气对新生儿呼吸窘迫综合征的临床疗效[J]. 国际呼吸杂志, 2016, 36(18): 1399-1402.
    高淑强, 巨容, 胡旭红, 等. 高频振荡通气联合西地那非治疗新生儿持续肺动脉高压的疗效观察[J]. 中华实用儿科临床杂志, 2015, 30(2): 114-117.
    CHEN D M, WU L Q, WANG R Q. Efficiency of high-frequency oscillatory ventilation combined with pulmonary surfactant in the treatment of neonatal meconium aspiration syndrome[J]. Int J Clin Exp Med, 2015, 8(8): 14490-14496.
    李艳秋, 王丹, 李建军. 肺泡表面活性物质治疗新生儿呼吸窘迫综合征的临床疗效观察[J]. 医学综述, 2019, 25(15): 3111-3115.
    WHITSETT J A, WERT S E, WEAVER T E. Diseases of pulmonary surfactant homeostasis[J]. Annu Rev Pathol, 2015, 10: 371-393.
    胡佳, 刘玲, 陈姝姝, 等. 肺表面活性物质联合机械通气治疗新生儿呼吸窘迫综合征30例临床观察[J]. 贵州医药, 2015, 39(11): 1003-1004.
    张方平, 吴龙艳, 高彧. 肺表面活性物质在早产儿呼吸窘迫综合征整体护理中的应用效果分析[J]. 贵州医药, 2018, 42(9): 1149-1150.
    冯爱民, 谢秀春, 王苗, 等. 肺表面活性物质联合无创高频振荡通气治疗新生儿呼吸窘迫综合征的效果观察[J]. 河北医学, 2019, 25(3): 551-555.
    LIN X Z, LAI J D, LV M, et al. Clinical efficacy of high-frequency oscillatory ventilation combined with pulmonary surfactant in treatment of neonatal pulmonary hemorrhage[J]. Chinese J Contemp Pediatr, 2015, 17(4): 345-349.
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