Clinical analysis of hyperbaric oxygen combined with vitamin C in patients with ACOP and its effect on myocardial markers and antioxidant levels

XIE Jing; XU Lixia; LYU Aihong

doi:10.7619/jcmp.202014025

Journal of Clinical Medicine in Practice > 2020 > 24(14): 94-96. > DOI: 10.7619/jcmp.202014025

XIE Jing, XU Lixia, LYU Aihong. Clinical analysis of hyperbaric oxygen combined with vitamin C in patients with ACOP and its effect on myocardial markers and antioxidant levels[J]. Journal of Clinical Medicine in Practice, 2020, 24(14): 94-96. DOI: 10.7619/jcmp.202014025

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Clinical analysis of hyperbaric oxygen combined with vitamin C in patients with ACOP and its effect on myocardial markers and antioxidant levels

1. Department of Emergency, Second Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, 450000;
2. Cardiovascular Department, Zhengzhou City Second People's Hospital, Zhengzhou, Henan, 450000;
3. Department of Neurology, Zhengzhou City First People's Hospital, Zhengzhou, Henan, 450000

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Received Date: March 20, 2020

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Objective To explore effect of hyperbaric oxygen combined with vitamin C in the treatment of patients with acute carbon monoxide poisoning(ACOP)and its effects on myocardial markers and antioxidant levels. Methods According to the random number table method, 46 patients with ACOP were divided into two groups, with 23 cases in each group. The control group was treated with hyperbaric oxygen, while the observation group was additionally given vitamin C on the basis of the control group. The total clinical efficacy, the levels of creatine kinase isoenzyme(CK-MB), brain natriuretic peptide(BNP), cardiac troponin I(cTnI)before and after treatment, catalase(CAT)and serum lipid peroxide(LPO)before and after treatment were observed. Results The total effective rate in the observation group was 95.65%, which was significantly higher than 73.91% in the control group(P<0.05); the levels of CK-MB, BNP and cTnI in the observation group were significantly lower than those in the control group(P<0.05); levels of LPO and CAT after treatment in the observation group were significantly lower than those in the control group(P<0.05). Conclusion Hyperbaric oxygen combined with vitamin C in patients with ACOP can improve the efficacy, reduce free radicals, and shorten the length of hospital stay.
- acute carbon monoxide poisoning,
- hyperbaric oxygen,
- vitamin C,
- catalase,
- B-type natriuretic peptide,
- creatine kinase isoenzyme,
- cardiac troponin I

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于娌. 高压氧治疗急性一氧化碳中毒的临床疗效及对并发症的影响[J]. 当代医学, 2018, 24(33): 109-111.

代明岩. 高压氧舱联合舒血宁在一氧化碳中毒急救中的应用效果[J]. 实用中西医结合临床, 2018, 18(5): 27-28.

靳丽丽, 郄涛, 张同乐, 等. CK-MB、cTnI、BNP、BUN、胱抑素在一氧化碳中毒患者中的预后价值[J]. 中国医药导报, 2019, 16(8): 136-139.

邹莉, 孟祥武, 郑龙, 等. 地塞米松、脑苷肌肽联合高压氧舱治疗一氧化碳中毒的早期临床疗效分析[J]. 湖北民族学院学报: 医学版, 2019, 36(2): 15-18.

付连杰. 高压氧舱治疗的临床护理方法及效果分析[J]. 继续医学教育, 2019, 33(9): 123-124.

赵艺, 孙秋岩. 高压氧治疗CO中毒性心脏病的效果分析[J]. 中国社区医师, 2019, 35(34): 42-43.

许顺. 神经生长因子辅助治疗一氧化碳中毒的效果评价[J]. 中外医学研究, 2019, 17(25): 128-129.

王全芳. 一氧化碳中毒患者的急诊急救观察及治疗[J]. 世界最新医学信息文摘, 2019, 19(A3): 103-104.

邵炜慧. 醒脑静联合高压氧对急性一氧化碳中毒患者治疗效果及对肝肾功能影响的分析[J]. 山西医药杂志, 2019, 48(18): 2253-2255.

薛琴芬, 王艳玲, 杨洋. 急性一氧化碳中毒患者应用高压氧治疗的护理干预效果分析[J]. 检验医学与临床, 2020, 17(2), 224-226.

衣洪杰, 郑成刚. 高压氧对妊娠大鼠一氧化碳中毒的疗效及对子代学习记忆能力的影响[J]. 第二军医大学学报, 2019(4): 408-411.

郑国文. 探讨52例急性一氧化碳中毒患者的急诊治疗体会[J]. 临床医药文献电子杂志, 2019, 6(66): 94-95.

吴薇, 彭小岭, 杨卜凡, 等. 高压氧治疗一氧化碳中毒迟发性脑病疗效的系统评价[J]. 华西医学, 2019, 34(10): 1126-1133.

解青松, 申法涛. 盐酸多奈哌齐联合高压氧治疗一氧化碳中毒迟发性脑病的临床研究[J]. 右江医学, 2019, 47(5): 370-372.

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