The imaging features of early-onset congenital syphilis

LU Yueyue; MA Quanmei; XIN Jun

doi:10.7619/jcmp.20201429

Journal of Clinical Medicine in Practice > 2021 > 25(4): 22-25. > DOI: 10.7619/jcmp.20201429

LU Yueyue, MA Quanmei, XIN Jun. The imaging features of early-onset congenital syphilis[J]. Journal of Clinical Medicine in Practice, 2021, 25(4): 22-25. DOI: 10.7619/jcmp.20201429

Citation:

LU Yueyue, MA Quanmei, XIN Jun. The imaging features of early-onset congenital syphilis[J]. Journal of Clinical Medicine in Practice, 2021, 25(4): 22-25. DOI: 10.7619/jcmp.20201429

Citation:

LU Yueyue, MA Quanmei, XIN Jun. The imaging features of early-onset congenital syphilis[J]. Journal of Clinical Medicine in Practice, 2021, 25(4): 22-25. DOI: 10.7619/jcmp.20201429

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The imaging features of early-onset congenital syphilis

Department of Radiology, Shengjing Hospital of China Medical University, Shenyang, Liaoning, 110004

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Received Date: November 10, 2020
Available Online: March 14, 2021
Published Date: February 27, 2021

Graphical Abstract

Abstract

Abstract

Objective To evaluate the value of imaging in diagnosing early congenital syphilis.
Methods The clinical and imaging data of children with serum tests positive for early congenital syphilis were retrospectively analyzed.
Results Out of 43 children, 24 males and 19 females were included in the study. The clinical lesions involved multiple systems and organs, with skin lesions[29 cases (67.4%)] being the most common. All forty-three children had imaging changes, mainly involving the long bones of the limbs, and the affected parts were mostly symmetrical, including 42 cases (97.7%) involving in the femur, 39 cases (90.7%) in the tibia and fibula, 16 cases (37.2%) of the humerus, 15 cases (34.9%) in radius and ulna. The main manifestation of bone damage was metaphysitis in 35 cases (81.4%), including 24 cases (55.8%)revealing typical "sandwich cake" sign, 11 cases (25.6%) with Wimberger sign, 23 cases (53.5%) with periostitis, and 8 cases of osteomyelitis (18.6%).
Conclusion Children with early congenital syphilis have typical imaging findings, and imaging can assist early clinical diagnosis thereby improving prognosis. Computed tomography (CT) and magnetic resonance imaging (MRI) are more sensitive, clear and intuitive than X-rays.
- congenital syphilis,
- X-ray examination,
- computed tomography,
- magnetic resonance imaging,
- imaging features

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References

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