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FENG Yuhong, BAI Yibao, HUANG Wenqin. Clinical efficacy of non-convulsive electric shock combined with anti-psychotic drugs in the treatment of hospitalized patients with schizophrenia[J]. Journal of Clinical Medicine in Practice, 2020, 24(17): 92-95. DOI: 10.7619/jcmp.202017025
Citation: FENG Yuhong, BAI Yibao, HUANG Wenqin. Clinical efficacy of non-convulsive electric shock combined with anti-psychotic drugs in the treatment of hospitalized patients with schizophrenia[J]. Journal of Clinical Medicine in Practice, 2020, 24(17): 92-95. DOI: 10.7619/jcmp.202017025
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Clinical efficacy of non-convulsive electric shock combined with anti-psychotic drugs in the treatment of hospitalized patients with schizophrenia

  • 1. Department of Women's Mental Health, The Fifth Hospital of Yulin City in Shaanxi Province, Yulin, Shaanxi, 719000;

  • 2. Department of Psychiatry, The Fifth Hospital of Yulin City in Shaanxi Province, Yulin, Shaanxi, 719000

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  • Received Date: June 21, 2020
  • Available Online: September 29, 2020
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    • Abstract
  • Objective To observe the clinical effect of non-convulsive electric shock combined with anti-psychotic drugs in treatment of hospitalized patients with schizophrenia. Methods A total of 90 patients with schizophrenia were selected as research objects, and were divided into experimental group(n=45)and control group(n=45)according to random number table method. The control group was treated with routine antipsychotic drugs, and the experimental group was treated with routine antipsychotic drugs combined with non-convulsive electric shock, both groups were observed for 6 weeks. The clinical efficacy and changes of cognitive function of the two groups were compared. Results The total clinical effective rate was 95.56%, which was significantly higher than 80.00%(P<0.05). There was no significant difference in Negative and Positive Symptom Scale(PANSS)score between the two groups before treatment(P>0.05); after 1 week 3 and 6 weeks of treatment, the PANSS scores of the two groups were significantly lower than those before treatment(P<0.05), and the experimental group was significantly lower than the control group(P<0.05). There was no significant difference in Wechsler Adult Intelligence Scale(WAIS-RC)score between the two groups before treatment(P>0.05); after 6 weeks of treatment, the WAIS-RC scores of both groups were significantly higher than before treatment(P<0.05), and the experimental group was significantly higher than that of the control group(P<0.05). Conclusion Non-convulsive electric shock combined with anti-psychotic drugs has better efficacy, which can significantly reduce the degree of cognitive function - injury caused by drug, enhance safety and compliance.
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