Research progress of targeted therapy for cervical cancer by tumor-associated macrophages

Tumor associated macrophages (TAM) are important immune cells in the tumor microenvironment (TME), which can secrete a variety of cytokines to participate in and regulate the biological behavior of cervical cancer (CC). A detailed understanding of the mechanism of TAM affecting the growth and metastasis of CC is the key to the development of targeted therapies. In this paper, the progress of TAM treatment in CC was reviewed in recent years, and the potential therapeutic targets, vaccines and drugs for TAM targeted treatment of CC were mainly discussed, which may provide theoretical basis for the research and development of novel targeted drugs for CC, in order to improve the quality of life and prolong the survival time of patients.