Analysis of clinical features of diabetes mellitus complicated with non-small cell lung cancer and its risk factors

  Objective   To analyze the clinical features of diabetes mellitus combined with non-small cell lung cancer and its risk factors.

  Methods   A total of 62 patients with diabetes mellitus complicated with non-small cell lung cancer were prospectively selected as combined group, and 161 patients with simple non-small cell lung cancer were selected as control group during the same period. Baseline data, clinical features and other relevant data were compared between the two groups; the risk factors of diabetes mellitus complicated with non-small cell lung cancer were analyzed.

  Results   The incidence of chest and back pain, fasting blood glucose (FPG) and triglyceride (TG) in the combined group were significantly higher than those in the control group, while high density lipoprotein cholesterol (HDL-C) was significantly lower than that in the control group (P < 0.05). Smoking history and basic diseases of respiratory system were risk factors for diabetes mellitus combined with non-small cell lung cancer (OR>1, P < 0.05).

  Conclusion   Diabetes mellitus combined with non-small cell lung cancer has no specific performance in clinical attack, and adenocarcinoma accounted for the highest proportion of pathological types, and most of them are poorly differentiated. Smoking history and basic diseases of respiratory system are risk factors for diabetes mellitus complicated with non-small cell lung cancer.