Value of magnetic resonance diffusion weighted imaging combined with perfusion weighted imaging in predicting final infarct volume of tumor-like cerebral infarction

XU Haifeng; CHEN Kemin; ZHANG Yongli; WEN Feng; QIAN Bangwei

doi:10.7619/jcmp.20211419

Journal of Clinical Medicine in Practice > 2021 > 25(11): 4-7, 38. > DOI: 10.7619/jcmp.20211419

XU Haifeng, CHEN Kemin, ZHANG Yongli, WEN Feng, QIAN Bangwei. Value of magnetic resonance diffusion weighted imaging combined with perfusion weighted imaging in predicting final infarct volume of tumor-like cerebral infarction[J]. Journal of Clinical Medicine in Practice, 2021, 25(11): 4-7, 38. DOI: 10.7619/jcmp.20211419

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Value of magnetic resonance diffusion weighted imaging combined with perfusion weighted imaging in predicting final infarct volume of tumor-like cerebral infarction

1.
Department of Radiology, People's Hospital of Pudong New Area in Shanghai City, Shanghai, 201299
2.
Department of Radiology, Ruijin Hospital Affiliated to Medical College of Shanghai Jiaotong University, Shanghai, 200025

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Received Date: March 30, 2021
Available Online: June 14, 2021
Published Date: June 14, 2021

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Abstract

Abstract

Objective To analyze the value of magnetic resonance diffusion weighted imaging (DWI) combined with perfusion weighted imaging (PWI) in predicting the final infarct volume of tumor-like cerebral infarction.
Methods DWI and PWI of 31 patients with tumor-like cerebral infarction confirmed by tracking magnetic resonance imaging (MRI) were retrospectively analyzed. The indexes such as relative cerebral blood flow (rCBF), relative cerebral blood volume (rCBV), relative mean transit time (rMTT) and relative apparent diffusion coefficient (rADC) of infarction center, prediction error area and ischemic penumbra were measured and calculated, and the differences between predicted infarction center volume and actual infarction center volume were compared.
Results Tukey post-event efficacy test showed that there were significant differences in rCBF and rCBV between final infarction, predicted error area and ischemic penumbra (P < 0.01), and there was a significant difference in rADC between final infarction and ischemic penumbra (P < 0.01). PWI was more sensitive than DWI in predicting irreversible injury of tumor-like cerebral infarction, and sensitivity of rCBF was the highest. Tracking MRI showed that there were 27 cases with hemorrhagic transformation (HT) and hemosiderosis (87.10%). The mean final infarction volume was (20.8±11.9) cm³, which was significantly lower than (25.9±10.6) cm³ of predicted infarction volume (t=7.682, P < 0.001). Correlation test showed that thefinal infarction volume was positively correlated with the predicted infarction volume (r=0.953, P < 0.001).
Conclusion The final infarction volume of tumor-like cerebral infarction is smaller than the predicted infarction volume, which may be related to the high incidence of HT or reperfusion. The sensitivity of rCBF is the highest when DWI and PWI are used to predict irreversible damage.
- magnetic resonance imaging,
- ischemic stroke,
- cerebral infarction volume,
- diffusion weighted imaging,
- perfusion weighted imaging

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Value of magnetic resonance diffusion weighted imaging combined with perfusion weighted imaging in predicting final infarct volume of tumor-like cerebral infarction

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