Effect of Huangbai Honghua Powder in preventing antitumor drug-related phlebitis

  Objective  To observe effect of Huangbai Honghua Powder in preventing phlebitis caused by antitumor drugs.

  Methods  A total of 270 patients using anti-tumor drugs were randomly divided into three groups. A group (n=90) used Huangbai Honghua Powder for external application, B group (n=90) used hydrocortisone butyrate cream for external application, and C group (n=90) used external application of hydrocortisone butyrate cream and Huangbai Honghua Powder. The incidence of phlebitis and the occurrence of pain in the three groups were observed.

  Results  The incidence rates of phlebitis and pain in the group C showed significant differences when compared with those in the groups A and B (P < 0.05).

  Conclusion  External application of hydrocortisone butyrate cream and Huangbai Honghua Powder can effectively prevent the occurrence of antitumor drug-related phlebitis, and is higher in safety.