Clinical study of modified urethral enucleation combined with cystostomy in the treatment of elderly prostatic hyperplasia patients

  Objective   To observe the clinical effect of modified urethral enucleation (M-PKEP) combined with cystostomy in the treatment of elderly prostatic hyperplasia (BPH) patients.

  Methods   A total of 119 patients diagnosed as BPH and given treatment were selected as study subjects, and were randomly divided into observation group (n=60, M-PKEP combined with cystostomy) and the control group (n=59, M-PKEP). The treatment effects, quality of life, international prostate symptom score (IPSS) and occurrence of complications between the two groups were compared, and influencing factors for improvement of symptoms in postoperative urine storage period were analyzed.

  Results   After treatment, the maximum urinary flow rate (Q_max) was significantly increased, and the residual urine volume (RUV) and IPSS storage score(IPSS-S) were significantly decreased in the two groups, and the improvement degree was more obvious in the observation group (P < 0.05). There was no difference in incidence of complications between the two groups (P>0.05). Age (≥80 years), detrusor contractibility (≥40 cmH₂O), residual urine volume (≥100 mL), nocturia frequency (≥2 times) were all independent risk factors affecting the IPSS-S of patients.

  Conclusion   M-PKEP combined with cystostomy in the treatment of elderly BPH patients has a good curative effect. It is suggested that timely intervention on detrusor contractility, RUV and nocturia frequency after surgery can improve theirquality of life.